RNA-guided isomerization of uridine to pseudouridine—pseudouridylation
YT Yu, UT Meier - RNA biology, 2014 - Taylor & Francis
Box H/ACA ribonucleoproteins (RNPs), each consisting of one unique guide RNA and 4
common core proteins, constitute a family of complex enzymes that catalyze, in an RNA …
common core proteins, constitute a family of complex enzymes that catalyze, in an RNA …
Human dyskerin: beyond telomeres
A Angrisani, R Vicidomini, M Turano, M Furia - Biological Chemistry, 2014 - degruyter.com
Human dyskerin is an evolutively conserved protein that participates in diverse nuclear
complexes: the H/ACA snoRNPs, that control ribosome biogenesis, RNA pseudouridylation …
complexes: the H/ACA snoRNPs, that control ribosome biogenesis, RNA pseudouridylation …
Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control
J Bizarro, C Charron, S Boulon, B Westman… - Journal of Cell …, 2014 - rupress.org
In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the
sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are …
sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are …
Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction
B Rothé, JM Saliou, M Quinternet, R Back… - Nucleic acids …, 2014 - academic.oup.com
Biogenesis of eukaryotic box C/D small nucleolar ribonucleoprotein particles (C/D
snoRNPs) involves conserved trans-acting factors, which are proposed to facilitate the …
snoRNPs) involves conserved trans-acting factors, which are proposed to facilitate the …
Characterization of the interaction between protein Snu13p/15.5 K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly
The yeast Snu13p protein and its 15.5 K human homolog both bind U4 snRNA and box C/D
snoRNAs. They also bind the Rsa1p/NUFIP assembly factor, proposed to scaffold immature …
snoRNAs. They also bind the Rsa1p/NUFIP assembly factor, proposed to scaffold immature …
RNA mimicry by the fap7 adenylate kinase in ribosome biogenesis
During biogenesis of the 40S and 60S ribosomal subunits, the pre-40S particles are
exported to the cytoplasm prior to final cleavage of the 20S pre-rRNA to mature 18S rRNA …
exported to the cytoplasm prior to final cleavage of the 20S pre-rRNA to mature 18S rRNA …
Progress in structural studies of telomerase
Highlights•Electron microscopy structure and subunit architecture of Tetrahymena
telomerase holoenzyme.•The electron microscopy structure of human telomerase.•First …
telomerase holoenzyme.•The electron microscopy structure of human telomerase.•First …
Identifizierung, funktionelle Charakterisierung und Tumor-Relevanz häufiger Kopiezahl-Veränderungen beim humanen Prostatakarzinom
A Krohn - 2014 - ediss.sub.uni-hamburg.de
Die Zielsetzungen der vorliegenden Arbeit waren die Identifizierung der Kopiezahl-
Veränderungen beim Prostatakarzinom mit der hochauflösenden SNP-Array Technologie …
Veränderungen beim Prostatakarzinom mit der hochauflösenden SNP-Array Technologie …