The NF-κB signal transduction pathway is best known as a major regulator of innate and
adaptive immune responses, yet there is a growing appreciation of its importance in immune …

Cancer and inflammation are intimately linked due to specific oxidative processes in the
tumor microenvironment. Lipoxygenases are a versatile class of oxidative enzymes involved …

Doxorubicin (DOX) is one of the most effective chemotherapeutic drugs; however, its
incidence of cardiotoxicity compromises its therapeutic index. Chrysin, a natural flavone …

Macrophages are sentinel immune cells that survey the tissue microenvironment, releasing
cytokines in response to both exogenous insults and endogenous events such as …

Hsp90 binding immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking
and hormone-dependent biological responses. With the purpose to expand this model to …

Die Besorgnis über die Entstehung bakterieller Resistenzen sowie vor einem möglichen
Transfer von Antibiotika-Resistenzgenen führte im Jahr 2006 zu einem europaweiten Verbot …

To understand the molecular mechanisms of parasitism in vivo, it is essential to elucidate
how the transcriptomes of the human hosts and the infecting parasites affect one another …

Acute lung injury (ALI) from a variety of clinical disorders, characterized by diffuse
inflammation, is a cause of acute respiratory failure that develops in patients of all ages …

This study aimed to evaluate the cell growth inhibition activity of açai (Euterpe oleracea
Mart.) polyphenolic extract against colon cancer HT-29 and SW-480 cells and the …

The family of A20-Binding Inhibitors of NF-κB (ABINs) consists of three proteins, ABIN-1,
ABIN-2 and ABIN-3, which were originally identified as A20-binding proteins and inhibitors …