Although several research strategies have been developed in the last decades, the current
therapeutic options for the treatment of Alzheimer's disease are limited to three …

Long-term cocaine use is a risk factor for the onset of neurocognitive impairment. This study
sought to determine whether the cholinesterase inhibitor rivastigmine could improve …

Актуальность темы исследования. Органические производные пятивалентного
фосфора (фосфорорганические соединения, ФОС) широко применяются в …

Heroin is the main abused opioid, and is causing most drug use related deaths in the
European Union and in the USA. New treatment strategies for heroin addiction are needed …

Purpose: The synthesis of eight new benzimidazole derivatives bearing dithiocarbamate
moiety and subsequently their anticholinesterase activity evaluations were aimed in this …

RNA recognition motif (RRM) is the most abundant RNA-binding domain, mainly known to
involve in post-transcriptional regulation processes like splicing stability and intracellular …

A doença de Alzheimer (DA) é a principal causa de demência nos idosos. Patologicamente,
é caracterizada pela presença de placas senis (PS) e emaranhados neurofibrilares (NFTs) …