Overview of microneedle system: a third generation transdermal drug delivery approach

MS Giri Nandagopal, R Antony… - Microsystem …, 2014 - Springer
Transdermal drug delivery has given cardinal contribution to medical practices. First-
generation transdermal delivery of small, lipophilic, low-dose drugs and second-generation …

Nanostructured lipid carrier-loaded hyaluronic acid microneedles for controlled dermal delivery of a lipophilic molecule

SG Lee, JH Jeong, KM Lee, KH Jeong… - International journal …, 2014 - Taylor & Francis
Nanostructured lipid carriers (NLCs) were employed to formulate a lipophilic drug into
hydrophilic polymeric microneedles (MNs). Hyaluronic acid (HA) was selected as a …

Improving fat graft survival through preconditioning of the recipient site with microneedling

B Sezgin, S Ozmen, H Bulam, S Omeroglu… - Journal of Plastic …, 2014 - Elsevier
Although fat grafts are considered the ideal soft-tissue fillers, the main concern dealing with
this technique is not being able to predict long-term graft survival due to high absorption …

Enhancement of the in vitro penetration of quercetin through pig skin by combined microneedles and lipid microparticles

R Paleco, SR Vučen, AM Crean, A Moore… - International journal of …, 2014 - Elsevier
Silicon microneedle patches were investigated, alone or in combination with lipid
microparticles (LMs), as a system to improve the in vitro skin penetration of the antioxidant …

The combination of microneedles with electroporation and sonophoresis to enhance hydrophilic macromolecule skin penetration

M Petchsangsai, T Rojanarata… - Biological and …, 2014 - jstage.jst.go.jp
The objective of the present work was to investigate the effects of 3 combinatorial techniques
(microneedle (MN), electroporation (EP), and sonophoresis (SN)) on the in vitro skin …

Core–shell nanocarriers for cancer therapy. Part I: biologically oriented design rules

I d'Angelo, C Conte, A Miro, F Quaglia… - Expert Opinion on Drug …, 2014 - Taylor & Francis
Introduction: The application of nanotechnologies to the cancer field for therapeutic, imaging
or diagnostic purposes represents an advanced and very attractive approach to overcome …

[HTML][HTML] Microneedle/nanoencapsulation-mediated transdermal delivery: Mechanistic insights

YA Gomaa, MJ Garland, FJ McInnes… - European Journal of …, 2014 - Elsevier
A systematic study was undertaken to gain more insight into the mechanism of transdermal
delivery of nanoencapsulated model dyes across microneedle (MN)-treated skin, a complex …

Microprojection arrays to immunise at mucosal surfaces

CL McNeilly, ML Crichton, CA Primiero… - Journal of controlled …, 2014 - Elsevier
The buccal mucosa (inner cheek) is an attractive site for delivery of immunotherapeutics,
due to its ease of access and rich antigen presenting cell (APC) distribution. However, to …

Irradiation with a low-level diode laser induces the developmental endothelial locus-1 gene and reduces proinflammatory cytokines in epithelial cells

T Fujimura, A Mitani, M Fukuda, M Mogi… - Lasers in Medical …, 2014 - Springer
We demonstrated previously that low-level diode laser irradiation with an indocyanine green-
loaded nanosphere coated with chitosan (ICG-Nano/c) had an antimicrobial effect, and thus …

Labeling the oily core of nanocapsules and lipid-core nanocapsules with a triglyceride conjugated to a fluorescent dye as a strategy to particle tracking in biological …

LA Fiel, RV Contri, JF Bica, F Figueiró… - Nanoscale research …, 2014 - Springer
The synthesis of novel fluorescent materials represents a very important step to obtain
labeled nanoformulations in order to evaluate their biological behavior. The strategy of …