Hydrogen sulfide activation in hemeproteins: the sulfheme scenario

BB Ríos-González, EM Román-Morales, R Pietri… - Journal of inorganic …, 2014 - Elsevier
Traditionally known as a toxic gas, hydrogen sulfide (H 2 S) is now recognized as an
important biological molecule involved in numerous physiological functions. Like nitric oxide …

Philosophy of voltage-gated proton channels

TE DeCoursey, J Hosler - Journal of The Royal Society …, 2014 - royalsocietypublishing.org
In this review, voltage-gated proton channels are considered from a mainly teleological
perspective. Why do proton channels exist? What good are they? Why did they go to such …

pH-dependent random coil 1H, 13C, and 15N chemical shifts of the ionizable amino acids: a guide for protein pK a measurements

G Platzer, M Okon, LP McIntosh - Journal of biomolecular NMR, 2014 - Springer
The p K a values and charge states of ionizable residues in polypeptides and proteins are
frequently determined via NMR-monitored pH titrations. To aid the interpretation of the …

Measurement of histidine pKa values and tautomer populations in invisible protein states

AL Hansen, LE Kay - … of the National Academy of Sciences, 2014 - National Acad Sciences
The histidine imidazole side chain plays a critical role in protein function and stability. Its
importance for catalysis is underscored by the fact that histidines are localized to active sites …

Histidine Adsorption on TiO2 Nanoparticles: An Integrated Spectroscopic, Thermodynamic, and Molecular-Based Approach toward Understanding Nano–Bio …

IA Mudunkotuwa, VH Grassian - Langmuir, 2014 - ACS Publications
Nanoparticles in biological media form dynamic entities as a result of competitive adsorption
of proteins on nanoparticle surfaces called protein coronas. The protein affinity toward …

Tautomerism in neutral histidine

C Bermúdez, S Mata, C Cabezas… - Angewandte …, 2014 - Wiley Online Library
Histidine is an important natural amino acid, involved in many relevant biological processes,
which, because of its physical properties, proved difficult to characterize experimentally in its …

Indirectly detected heteronuclear correlation solid-state NMR spectroscopy of naturally abundant 15N nuclei

SM Althaus, K Mao, JA Stringer, T Kobayashi… - Solid State Nuclear …, 2014 - Elsevier
Two-dimensional indirectly detected through-space and through-bond 1 H {15 N} solid-state
NMR experiments utilizing fast magic angle spinning (MAS) and homonuclear multipulse 1 …

[PDF][PDF] Capturing a reactive state of amyloid aggregates

S Parthasarathy, B Yoo, D McElheny, W Tay… - Journal of Biological …, 2014 - ASBMB
The interaction of redox-active copper ions with misfolded amyloid β (Aβ) is linked to
production of reactive oxygen species (ROS), which has been associated with oxidative …

2D IR spectroscopy of histidine: probing side-chain structure and dynamics via backbone amide vibrations

A Ghosh, MJ Tucker, F Gai - The Journal of Physical Chemistry B, 2014 - ACS Publications
It is well known that histidine is involved in many biological functions due to the structural
versatility of its side chain. However, probing the conformational transitions of histidine in …

Artificial nucleobase–amino acid conjugates: a new class of TAR RNA binding agents

JP Joly, G Mata, P Eldin, L Briant… - … A European Journal, 2014 - Wiley Online Library
The human immunodeficiency virus type‐1 (HIV‐1) Tat protein stimulates transcriptional
elongation. Tat is involved in the transcription machinery by binding to the transactivation …