The radiation oncology community has witnessed growing interest in observational research
conducted using large-scale data sources such as registries and claims-based data sets …

Objectives To recommend methodological standards in the prevention and handling of
missing data for primary patient-centered outcomes research (PCOR). Study Design and …

Objectives The prevalence of rheumatoid arthritis (RA) and its current treatment practices in
Japan are poorly documented. Therefore, we examined these factors in a Japanese health …

Evidence-based health care decisions are best informed by comparisons of all relevant
interventions used to treat conditions in specific patient populations. Observational studies …

The clinical decision analysis (CDA) has used to overcome complexity and uncertainty in
medical problems. The CDA is a tool allowing decision-makers to apply evidence-based …

Objective To evaluate real-world treatment persistence among patients with type 2 diabetes
mellitus (T2DM) initiating treatment with insulin. Methods Patient-level data were pooled …

Study Design. A Markov state-transition model was developed to evaluate the cost-
effectiveness of anterior cervical discectomy and fusion (ACDF) and cervical disc …

We aimed to systematically review observational studies evaluating use of bisphosphonates
(BPs) and risk of osteonecrosis of jaw (ONJ) or other sites among non-cancer patients …

Real-world data (RWD) is an umbrella term for different types of data that are not collected in
conventional randomised controlled trials. RWD in the healthcare sector comes from various …

Research in respiratory, sleep, and critical care medicine has historically been the domain of
scientists and clinicians attempting to understand pathophysiological mechanisms and …