Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis
The nuclear receptor PPARγ is a master regulator of adipogenesis. PPARγ is highly
expressed in adipose tissues and its expression is markedly induced during adipogenesis …
expressed in adipose tissues and its expression is markedly induced during adipogenesis …
Molecular targets of aspirin and cancer prevention
L Alfonso, G Ai, RC Spitale, GJ Bhat - British journal of cancer, 2014 - nature.com
Salicylates from plant sources have been used for centuries by different cultures to treat a
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …
Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation
The emerging view of Nε-lysine acetylation in eukaryotes is of a relatively abundant post-
translational modification (PTM) that has a major impact on the function, structure, stability …
translational modification (PTM) that has a major impact on the function, structure, stability …
[HTML][HTML] Role of epithelial-mesenchymal transition in gastric cancer initiation and progression
Z Peng, CX Wang, EH Fang, GB Wang… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Gastric cancer is one of the most common malignant tumors worldwide. Due to its intricate
initiation and progression mechanisms, early detection and effective treatment of gastric …
initiation and progression mechanisms, early detection and effective treatment of gastric …
[HTML][HTML] Genome of brown tide virus (AaV), the little giant of the Megaviridae, elucidates NCLDV genome expansion and host–virus coevolution
Aureococcus anophagefferens causes economically and ecologically destructive “brown
tides” in the United States, China and South Africa. Here we report the 370,920 bp genomic …
tides” in the United States, China and South Africa. Here we report the 370,920 bp genomic …
Crafting the brain–role of histone acetyltransferases in neural development and disease
BN Sheikh - Cell and tissue research, 2014 - Springer
The human brain is a highly specialized organ containing nearly 170 billion cells with
specific functions. Development of the brain requires adequate proliferation, proper cell …
specific functions. Development of the brain requires adequate proliferation, proper cell …
The UmGcn5 gene encoding histone acetyltransferase from Ustilago maydis is involved in dimorphism and virulence
JM González-Prieto, R Rosas-Quijano… - Fungal Genetics and …, 2014 - Elsevier
We isolated a gene encoding a histone acetyltransferase from Ustilago maydis (DC.) Cda.,
which is orthologous to the Saccharomyces cerevisiae GCN5 gene. The gene was isolated …
which is orthologous to the Saccharomyces cerevisiae GCN5 gene. The gene was isolated …
Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation
Y Kong, M Grimaldi, E Curtin, M Dougherty… - Chemistry & biology, 2014 - cell.com
Cranial neural crest (CNC) cells are patterned and coalesce to facial prominences that
undergo convergence and extension to generate the craniofacial form. We applied a …
undergo convergence and extension to generate the craniofacial form. We applied a …
Proteolytic clipping of histone tails: the emerging role of histone proteases in regulation of various biological processes
Chromatin is a dynamic DNA scaffold structure that responds to a variety of external and
internal stimuli to regulate the fundamental biological processes. Majority of the cases …
internal stimuli to regulate the fundamental biological processes. Majority of the cases …
Multiple Complexes of Long Aliphatic N-Acyltransferases Lead to Synthesis of 2,6-Diacylated/2-Acyl-Substituted Glycopeptide Antibiotics, Effectively Killing …
Teicoplanin A2-2 (Tei)/A40926 is the last-line antibiotic to treat multidrug-resistant Gram-
positive bacterial infections, eg, methicillin-resistant Staphylococcus aureus (MRSA) and …
positive bacterial infections, eg, methicillin-resistant Staphylococcus aureus (MRSA) and …