Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine
Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …
Rare cell isolation and analysis in microfluidics
Rare cells are low-abundance cells in a much larger population of background cells.
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …
DNA nanoflowers for multiplexed cellular imaging and traceable targeted drug delivery
We present a facile approach to make aptamer‐conjugated FRET (fluorescent resonance
energy transfer) nanoflowers (NFs) through rolling circle replication for multiplexed cellular …
energy transfer) nanoflowers (NFs) through rolling circle replication for multiplexed cellular …
[HTML][HTML] Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model
The potential utility of circulating tumor cells (CTCs) to guide clinical care in oncology
patients has gained momentum with emerging micro-and nanotechnologies. Establishing …
patients has gained momentum with emerging micro-and nanotechnologies. Establishing …
SpyLigase peptide–peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture
JO Fierer, G Veggiani… - Proceedings of the …, 2014 - National Acad Sciences
Individual proteins can now often be modified with atomic precision, but there are still major
obstacles to connecting proteins into larger assemblies. To direct protein assembly, ideally …
obstacles to connecting proteins into larger assemblies. To direct protein assembly, ideally …
Micro total analysis systems: fundamental advances and biological applications
CT Culbertson, TG Mickleburgh… - Analytical …, 2014 - ACS Publications
It has been more than 20 years since the first micro total analysis systems (μTAS) papers
were published. Initial reports of these devices, which are also commonly referred to as …
were published. Initial reports of these devices, which are also commonly referred to as …
Multivalent capture and detection of cancer cells with DNA nanostructured biosensors and multibranched hybridization chain reaction amplification
Sensitive detection of cancer cells plays a critically important role in the early detection of
cancer and cancer metastasis. However, because circulating tumor cells are extremely rare …
cancer and cancer metastasis. However, because circulating tumor cells are extremely rare …
Towards XNA nanotechnology: new materials from synthetic genetic polymers
VB Pinheiro, P Holliger - Trends in biotechnology, 2014 - cell.com
Nucleic acids display remarkable properties beyond information storage and propagation.
The well-understood base pairing rules have enabled nucleic acids to be assembled into …
The well-understood base pairing rules have enabled nucleic acids to be assembled into …
Nanomaterials as signal amplification elements in DNA-based electrochemical sensing
L Wu, E Xiong, X Zhang, X Zhang, J Chen - Nano Today, 2014 - Elsevier
Signal amplification strategies have attracted considerable attention due to the growing
demands for ultrasensitive bioassays. Here, we summarize the latest developments in the …
demands for ultrasensitive bioassays. Here, we summarize the latest developments in the …
Dynamic Introduction of Cell Adhesive Factor via Reversible Multicovalent Phenylboronic Acid/cis-Diol Polymeric Complexes
In this work, dynamic introduction of bioactive RGD peptide on a matrix was successfully
demonstrated via reversible multicovalent interactions within PBA/cis-diol polymeric …
demonstrated via reversible multicovalent interactions within PBA/cis-diol polymeric …