The Biological Effects of Childhood Trauma - Child and Adolescent Psychiatric Clinics Skip to
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Validated biological and psychological markers of acute stress in humans are an important
tool in translational research. The Trier Social Stress Test (TSST), involving public interview …

Depression has been linked to increased cortisol reactivity and differences in limbic brain
volumes, yet the mechanisms underlying these alterations are unclear. One main hypothesis …

Early adverse experiences such as abuse or neglect can influence brain development and
consequently bring forth a predisposition toward mental and behavioral disorders. Many …

The hypothalamus-pituitary-adrenal axis (HPA) is essential in the regulation of stress
responses. Increased methylation of the promoter region of the glucocorticoid receptor gene …

Die uralte Beziehung zwischen Mensch und Tier hat in jüngerer Zeit durch den Einsatz von
Tieren in Therapie und Pädagogik neues Interesse geweckt. Tiergestützte Interventionen …

Background and aims Childhood trauma may have longstanding effects on individuals'
propensity to react adversely to stress, and also predisposes individuals to suffer from …

Recent evidence suggests that early life stress (ELS) changes stress reactivity via reduced
resting state functional connectivity (rsFC) between amygdala and the prefrontal cortex …

Child maltreatment often has a negative impact on the development of social behavior and
health. The biobehavioral mechanisms through which these adverse outcomes emerge …

We evaluate the association between subtypes of early life stress (ELS; sexual abuse,
physical abuse, emotional abuse, physical neglect, and emotional neglect) and psychiatric …