Type 1 diabetes mellitus and cardiovascular disease: a scientific statement from the American Heart Association and American Diabetes Association

SD De Ferranti, IH De Boer, V Fonseca, CS Fox… - Circulation, 2014 - Am Heart Assoc
(CVD) in individuals with type 1 diabetes mellitus (T1DM), the pathophysiology underlying
the relationship between cardiovascular events, CVD risk factors, and T1DM is not well …

Targeting inflammation in the treatment of type 2 diabetes: time to start

MY Donath - Nature reviews Drug discovery, 2014 - nature.com
The role of inflammation in the pathogenesis of type 2 diabetes and associated
complications is now well established. Several conditions that are driven by inflammatory …

Antioxidants and human diseases

P Rajendran, N Nandakumar, T Rengarajan… - Clinica chimica acta, 2014 - Elsevier
Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …

[PDF][PDF] Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk …

G Danaei, Y Lu, GM Singh… - Lancet Diabetes & …, 2014 - observatorio.fm.usp.br
Background High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors
for cardiovascular diseases and some of these factors also increase the risk of chronic …

Anti-inflammatory strategies for ventricular remodeling following ST-segment elevation acute myocardial infarction

IM Seropian, S Toldo, BW Van Tassell… - Journal of the American …, 2014 - jacc.org
Acute myocardial infarction (AMI) leads to molecular, structural, geometric, and functional
changes in the heart in a process known as ventricular remodeling. An intense organized …

The role of oxidative stress and inflammation in cardiovascular aging

J Wu, S Xia, B Kalionis, W Wan… - BioMed research …, 2014 - Wiley Online Library
Age is an independent risk factor of cardiovascular disease, even in the absence of other
traditional factors. Emerging evidence in experimental animal and human models has …

Neutrophil to lymphocyte ratio in relation to risk of all-cause mortality and cardiovascular events among patients undergoing angiography or cardiac revascularization …

X Wang, G Zhang, X Jiang, H Zhu, Z Lu, L Xu - Atherosclerosis, 2014 - Elsevier
Objective The aim of this study was to investigate whether neutrophil to lymphocyte ratio
(NLR) was an independent predictor for all-cause mortality or cardiovascular events in …

A family-oriented psychosocial intervention reduces inflammation in low-SES African American youth

GE Miller, GH Brody, T Yu… - Proceedings of the …, 2014 - National Acad Sciences
Children of low socioeconomic status (SES) are at elevated risk for health problems across
the lifespan. Observational studies suggest that nurturant parenting might offset some of …

Inhibiting DNA methylation by 5-Aza-2′-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation

Q Cao, X Wang, L Jia, AK Mondal, A Diallo… - …, 2014 - academic.oup.com
Inflammation marks all stages of atherogenesis. DNA hypermethylation in the whole
genome or specific genes is associated with inflammation and cardiovascular diseases …

Functional stability of plasminogen activator inhibitor‐1

S Yasar Yildiz, P Kuru, E Toksoy Oner… - The scientific world …, 2014 - Wiley Online Library
Plasminogen activator inhibitor‐1 (PAI‐1) is the main inhibitor of plasminogen activators,
such as tissue‐type plasminogen activator (t‐PA) and urokinase‐type plasminogen activator …