[HTML][HTML] Suppression of RNA Silencing by a Plant DNA Virus Satellite Requires a Host Calmodulin-Like Protein to Repress RDR6 Expression

F Li, C Huang, Z Li, X Zhou - PLoS pathogens, 2014 - journals.plos.org
In plants, RNA silencing plays a key role in antiviral defense. To counteract host defense,
plant viruses encode viral suppressors of RNA silencing (VSRs) that target different effector …

Guest list or black list: heritable small RNAs as immunogenic memories

O Rechavi - Trends in Cell Biology, 2014 - cell.com
Small RNA-mediated gene silencing plays a pivotal role in genome immunity by recognizing
and eliminating viruses and transposons that may otherwise colonize the genome. However …

Viruses and RNA interference: issues and controversies

BR Cullen - Journal of virology, 2014 - Am Soc Microbiol
The question of whether any mammalian cells are able to mount an effective RNA
interference-mediated antiviral innate immune response has remained highly controversial …

Drosophila C virus systemic infection leads to intestinal obstruction

S Chtarbanova, O Lamiable, KZ Lee, D Galiana… - Journal of …, 2014 - Am Soc Microbiol
Drosophila C virus (DCV) is a positive-sense RNA virus belonging to the Dicistroviridae
family. This natural pathogen of the model organism Drosophila melanogaster is commonly …

Biological properties and expression strategy of rosellinia necatrix megabirnavirus 1 analysed in an experimental host, Cryphonectria parasitica

L Salaipeth, S Chiba… - Journal of general …, 2014 - microbiologyresearch.org
Rosellinia necatrix megabirnavirus 1 (RnMBV1) with a bipartite dsRNA genome (dsRNA1
and dsRNA2) confers hypovirulence to its natural host, the white root rot fungus, and is thus …

[HTML][HTML] Programmed ribosomal frameshift alters expression of west nile virus genes and facilitates virus replication in birds and mosquitoes

EB Melian, S Hall-Mendelin, F Du, N Owens… - PLoS …, 2014 - journals.plos.org
West Nile virus (WNV) is a human pathogen of significant medical importance with close to
40,000 cases of encephalitis and more than 1,600 deaths reported in the US alone since its …

[HTML][HTML] Tombusvirus-yeast interactions identify conserved cell-intrinsic viral restriction factors

Z Sasvari, P Alatriste Gonzalez, PD Nagy - Frontiers in Plant Science, 2014 - frontiersin.org
To combat viral infections, plants possess innate and adaptive immune pathways, such as
RNA silencing, R gene and recessive gene-mediated resistance mechanisms. However, it is …

Key elements of the RNAi pathway are regulated by hepatitis B virus replication and HBx acts as a viral suppressor of RNA silencing

M Chinnappan, AK Singh, PK Kakumani… - Biochemical …, 2014 - portlandpress.com
The host-mediated RNAi pathways restrict replication of viruses in plant, invertebrate and
vertebrate systems. However, comparatively little is known about the interplay between …

[HTML][HTML] Supervised learning classification models for prediction of plant virus encoded RNA silencing suppressors

Z Jagga, D Gupta - PloS one, 2014 - journals.plos.org
Viral encoded RNA silencing suppressor proteins interfere with the host RNA silencing
machinery, facilitating viral infection by evading host immunity. In plant hosts, the viral …

Robust RNA silencing‐mediated resistance to Plum pox virus under variable abiotic and biotic conditions

E Di Nicola, M Tavazza, A Lucioli… - Molecular plant …, 2014 - Wiley Online Library
Some abiotic and biotic conditions are known to have a negative impact on post‐
transcriptional gene silencing (PTGS), thus representing a potential concern for the …