Diabetic neuropathy: mechanisms, emerging treatments, and subtypes

JW Albers, R Pop-Busui - Current neurology and neuroscience reports, 2014 - Springer
Diabetic neuropathies (DNs) differ in clinical course, distribution, fiber involvement (type and
size), and pathophysiology, the most typical type being a length-dependent distal symmetric …

Painful diabetic neuropathy

A Peltier, SA Goutman, BC Callaghan - Bmj, 2014 - bmj.com
Diabetes is a worldwide epidemic, and associated neuropathy is its most costly and
disabling complication. Given the rising prevalence of painful diabetic neuropathy, it is …

Mouse models of diabetic neuropathy

PD O'Brien, SA Sakowski, EL Feldman - ILAR journal, 2014 - academic.oup.com
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes and is
associated with significant morbidity and mortality. DPN is characterized by progressive …

Mitotoxicity in distal symmetrical sensory peripheral neuropathies

GJ Bennett, T Doyle, D Salvemini - Nature Reviews Neurology, 2014 - nature.com
Chronic distal symmetrical sensory peripheral neuropathy is a common neurological
complication of cancer chemotherapy, HIV treatment and diabetes. Although aetiology …

Feline diabetes mellitus

CE Reusch - Canine and Feline Endocrinology, 4th ed.; Feldman …, 2014 - books.google.com
Prognosis, 308 hyperadrenocorticism and variable in the case of hypersomatotropism. Cats
are prone to stress hyperglycemia, which may cause difficulties in diagnosis and monitoring …

Length dependent loss of motor axons and altered motor unit properties in human diabetic polyneuropathy

MD Allen, K Kimpinski, TJ Doherty, CL Rice - Clinical Neurophysiology, 2014 - Elsevier
Objective To assess the number and properties of motor units in an upper and lower limb
muscle (tibialis anterior [TA] and first dorsal interosseous [FDI]) in human diabetic …

Channelopathies, painful neuropathy, and diabetes: which way does the causal arrow point?

JGJ Hoeijmakers, CG Faber, ISJ Merkies… - Trends in molecular …, 2014 - cell.com
Diabetes mellitus, a major global health problem, is commonly associated with painful
peripheral neuropathy, which can substantially erode quality of life. Despite its clinical …

Gender differences in nerve regeneration after sciatic nerve injury and repair in healthy and in type 2 diabetic Goto-Kakizaki rats

L Stenberg, LB Dahlin - BMC neuroscience, 2014 - Springer
Background In view of the global increase in diabetes, and the fact that recent findings
indicate that diabetic neuropathy is more frequently seen in males, it is crucial to evaluate …

Iron homeostasis in peripheral nervous system, still a black box?

S Levi, C Taveggia - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Iron is the most abundant transition metal in biology and an essential cofactor
for many cellular enzymes. Iron homeostasis impairment is also a component of peripheral …

Insights into the pathogenesis and treatment of painful diabetic neuropathy

M Greig, S Tesfaye, D Selvarajah… - Handbook of Clinical …, 2014 - Elsevier
Painful diabetic distal symmetrical polyneuropathy (painful DPN) is a puzzle with two
important missing pieces: Firstly we still do not understand why only some patients with …