Biodegradable polymers—an overview

S Doppalapudi, A Jain, W Khan… - Polymers for Advanced …, 2014 - Wiley Online Library
The revelation of biodegradable polymers dates back to many years ago. From then, their
emergence leads to the surge of many biomaterials applicable in various fields like …

Recent developments in scaffold-guided cartilage tissue regeneration

J Liao, K Shi, Q Ding, Y Qu, F Luo… - Journal of biomedical …, 2014 - ingentaconnect.com
Articular cartilage repair is one of the most challenging problems in biomedical engineering
because the regenerative capacity of cartilage is intrinsically poor. The lack of efficient …

[HTML][HTML] Paclitaxel-loaded polyphosphate nanoparticles: a potential strategy for bone cancer treatment

EM Alexandrino, S Ritz, F Marsico, G Baier… - Journal of Materials …, 2014 - pubs.rsc.org
While it has been shown that phosphates can target molecules and nanocarriers to bone we
herein demonstrate the preparation of polyphosphate nanoparticles loaded with paclitaxel …

Phosphorous-containing polymers for regenerative medicine

BM Watson, FK Kasper, AG Mikos - Biomedical Materials, 2014 - iopscience.iop.org
Disease and injury have resulted in a large, unmet need for functional tissue replacements.
Polymeric scaffolds can be used to deliver cells and bioactive signals to address this need …

Self-assembled nanoparticles based on the c(RGDfk) peptide for the delivery of siRNA targeting the VEGFR2 gene for tumor therapy

L Liu, X Liu, Q Xu, P Wu, X Zuo, J Zhang… - International journal …, 2014 - Taylor & Francis
The clinical application of small interfering RNA (siRNA) has been restricted by their poor
intracellular uptake, low serum stability, and inability to target specific cells. During the last …

Multifunctional hydrogels based on β-cyclodextrin with both biomineralization and anti-inflammatory properties

S Liu, X Chen, Q Zhang, W Wu, J Xin, J Li - Carbohydrate polymers, 2014 - Elsevier
In this study, a series of carboxylated hydrogels are synthesized using β-cyclodextrin,
epichlorohydrin and succinic anhydride. It is found that the carboxyl groups on the β …

Polyphosphoester-based nanoparticles with viscous flow core enhanced therapeutic efficacy by improved intracellular drug release

YC Ma, JX Wang, W Tao, HS Qian… - ACS Applied Materials & …, 2014 - ACS Publications
The intracellular drug release rate from the hydrophobic core of self-assembled
nanoparticles can significantly affect the therapeutic efficacy. Currently, the hydrophobic …

Synthesis and Self‐Assembly of Thermoresponsive Amphiphilic Biodegradable Polypeptide/Poly (ethyl ethylene phosphate) Block Copolymers

Q Wu, D Zhou, R Kang, X Tang, Q Yang… - Chemistry–An Asian …, 2014 - Wiley Online Library
We report the design and synthesis of new fully biodegradable thermoresponsive
amphiphilic poly (γ‐benzyl l‐glutamate)/poly (ethyl ethylene phosphate)(PBLG‐b‐PEEP) …

Biomaterials for scaffolds: Synthetic polymers

L Rojo, B Vázquez… - Scaffolds for Tissue …, 2014 - api.taylorfrancis.com
The increasing activity in regenerative medicine needs the contribution of specific and
functional biomaterials to achieve the main objective of this new discipline. General methods …

Design strategies and applications of citrate-based biodegradable elastomeric polymers

J Guo, DY Nguyen, RT Tran, Z Xie, X Bai… - Natural and Synthetic …, 2014 - Elsevier
Biodegradable elastomers have recently found numerous applications in diverse areas of
biomedical engineering, such as tissue engineering, drug delivery, gene delivery, and …