Toll-like receptors in central nervous system injury and disease: a focus on the spinal cord
Toll-like receptors (TLRs) are best known for recognizing pathogens and initiating an innate
immune response to protect the host. However, they also detect tissue damage and induce …
immune response to protect the host. However, they also detect tissue damage and induce …
TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling
The proinflammatory cytokines tumor necrosis factor (TNF) α and interleukin (IL) 1β have
been strongly implicated in the pathogenesis of neuropathic pain, but the intracellular …
been strongly implicated in the pathogenesis of neuropathic pain, but the intracellular …
Role of TLR4 in lipopolysaccharide-induced acute kidney injury: protection by blueberry
AR Nair, GS Masson, PJ Ebenezer, F Del Piero… - Free Radical Biology …, 2014 - Elsevier
Inflammation has been implicated in the pathophysiology of kidney disorders. Previous
studies have documented the contributions of various inflammatory cascades in the …
studies have documented the contributions of various inflammatory cascades in the …
Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection
PE Almeida, NR Roque, KG Magalhães… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The nuclear receptor PPARγ acts as a key modulator of lipid metabolism, inflammation and
pathogenesis in BCG-infected macrophages. However, the molecular mechanisms involved …
pathogenesis in BCG-infected macrophages. However, the molecular mechanisms involved …
Lipopolysaccharide enhances Wnt5a expression through toll-like receptor 4, myeloid differentiating factor 88, phosphatidylinositol 3-OH kinase/AKT and nuclear factor …
W He, Z Wang, Z Zhou, Y Zhang, Q Zhu, K Wei… - Journal of …, 2014 - Elsevier
Introduction Lipopolysaccharide (LPS) has been implicated in mesenchymal stem cell
differentiation processes. Wnt5a, one of the “non-canonical” Wnt family members, is …
differentiation processes. Wnt5a, one of the “non-canonical” Wnt family members, is …
The TLR 2 Ligand FSL‐1 and the TLR 5 Ligand Flagellin Mediate Pro‐Inflammatory and Pro‐Labour Response via MyD88/TRAF 6/NF‐κB‐Dependent Signalling
R Lim, G Barker, M Lappas - American Journal of Reproductive …, 2014 - Wiley Online Library
Problem Toll‐like receptors (TLR s) 2 and 5 induce inflammation via the adapter proteins
myeloid differentiation factor 88 (M y D 88) and TNFR‐associated factor 6 (TRAF 6) and the …
myeloid differentiation factor 88 (M y D 88) and TNFR‐associated factor 6 (TRAF 6) and the …
A blueberry-enriched diet improves renal function and reduces oxidative stress in metabolic syndrome animals: potential mechanism of TLR4-MAPK signaling …
AR Nair, CM Elks, J Vila, F Del Piero, DB Paulsen… - PLoS …, 2014 - journals.plos.org
Background Metabolic syndrome (MetS) is characterized by a cluster of health factors that
indicate a higher risk for cardio-renal diseases. Recent evidence indicates that antioxidants …
indicate a higher risk for cardio-renal diseases. Recent evidence indicates that antioxidants …
The role of interleukin-1 receptor-associated kinases in Vogt-Koyanagi-Harada disease
M Sun, P Yang, L Du, Y Yang, J Ye - PloS one, 2014 - journals.plos.org
Purpose To explore whether IRAK1 and IRAK4 are involved in the pathogenesis of Vogt-
Koyanagi-Harada (VKH) disease. Methods Thirty-nine VKH patients and thirty-two healthy …
Koyanagi-Harada (VKH) disease. Methods Thirty-nine VKH patients and thirty-two healthy …
Analysis of the Toll-like receptor 2-2 (TLR2-2) and TLR4 mRNA expression in the intestinal mucosal immunity of broilers fed on diets supplemented with nickel …
B Wu, H Cui, X Peng, J Fang, Z Zuo, J Deng… - International Journal of …, 2014 - mdpi.com
Toll-like receptor (TLRs) are important innate immune receptors, and TLR2 and TLR4 play
an important role in intestinal mucosal innate immunity. It has been found that nickel (Ni) can …
an important role in intestinal mucosal innate immunity. It has been found that nickel (Ni) can …
一种从大肠杆菌包涵体中分离纯化GST-TRAF6 融合蛋白的方法
张西轩， 李晔， 张振奇， 董世瑞， 赵培， 阮海华 - 生物技术通报, 2014 - biotech.aiijournal.com
利用8 mol/L 尿素溶液对表达在大肠杆菌包涵体中的GST-TRAF6 融合蛋白进行变性,
通过逐级稀释复性的方法对尿素溶解后的GST-TRAF6 融合蛋白进行复性, 将复性后的GST …
通过逐级稀释复性的方法对尿素溶解后的GST-TRAF6 融合蛋白进行复性, 将复性后的GST …