A novel stable isotope labelling assisted workflow for improved untargeted LC–HRMS based metabolomics research
C Bueschl, B Kluger, M Lemmens, G Adam… - Metabolomics, 2014 - Springer
Abstract Many untargeted LC–ESI–HRMS based metabolomics studies are still hampered
by the large proportion of non-biological sample derived signals included in the generated …
by the large proportion of non-biological sample derived signals included in the generated …
Metabolomics‐assisted refinement of the pathways of steroidal glycoalkaloid biosynthesis in the tomato clade
Steroidal glycoalkaloids (SGAs) are nitrogen‐containing secondary metabolites of the
Solanum species, which are known to have large chemical and bioactive diversity in nature …
Solanum species, which are known to have large chemical and bioactive diversity in nature …
Exploring the A rabidopsis sulfur metabolome
K Gläser, B Kanawati, T Kubo… - The Plant …, 2014 - Wiley Online Library
Sulfur plays a crucial role in protein structure and function, redox status and plant biotic
stress responses. However, our understanding of sulfur metabolism is limited to identified …
stress responses. However, our understanding of sulfur metabolism is limited to identified …
Revisiting anabasine biosynthesis in tobacco hairy roots expressing plant lysine decarboxylase gene by using 15N-labeled lysine
S Bunsupa, K Komastsu, R Nakabayashi… - Plant …, 2014 - jstage.jst.go.jp
Anabasine is an alkaloid found in a small number of Nicotiana species. The components of
the anabasine biosynthetic pathway have yet to be identified. Here, we report the …
the anabasine biosynthetic pathway have yet to be identified. Here, we report the …
Automated LC-HRMS (/MS) approach for the annotation of fragment ions derived from stable isotope labeling-assisted untargeted metabolomics
NKN Neumann, SM Lehner, B Kluger… - Analytical …, 2014 - ACS Publications
Structure elucidation of biological compounds is still a major bottleneck of untargeted LC-
HRMS approaches in metabolomics research. The aim of the present study was to combine …
HRMS approaches in metabolomics research. The aim of the present study was to combine …
Profiling of stable isotope enrichment in specialized metabolites using liquid chromatography and multiplexed nonselective collision-induced dissociation
Z Wang, AD Jones - Analytical chemistry, 2014 - ACS Publications
Engineering of specialized metabolites in plants, microbes, and other organisms is hindered
by significant knowledge gaps about metabolic pathways responsible for metabolite …
by significant knowledge gaps about metabolic pathways responsible for metabolite …
Metabolomics
Y Sawada, T Aoki - The Lotus japonicus Genome, 2014 - Springer
Metabolomics is an “omics” approach for the comprehensive profiling of the small molecules
in an organism, which has been made possible by recent advances in mass spectrometry …
in an organism, which has been made possible by recent advances in mass spectrometry …
Advanced applications of high performance Fourier transform ion cyclotron resonance mass spectrometry
J Wei - 2014 - wrap.warwick.ac.uk
Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) displays its
advances in obtaining high resolving power, high mass accuracy, and coupling with many …
advances in obtaining high resolving power, high mass accuracy, and coupling with many …
[PDF][PDF] ダイズ近縁種ツルマメのメタボローム情報を利用した代謝育種研究
澤田有司 - 大豆たん白質研究/不二たん白質研究振興財団[編], 2014 - fujifoundation.or.jp
統計解析ではメタボローム情報の全体像をとらえることは困難である. そこで最もサンプル間の差に
寄与する変数 (主成分) を探索的に調べる主成分解析を行った. この結果, 187 …
寄与する変数 (主成分) を探索的に調べる主成分解析を行った. この結果, 187 …
統合メタボロミクスによる有用植物資源の開発
中林亮， 浅野孝， 山崎真巳， 斉藤和季 - 化学と生物, 2014 - jstage.jst.go.jp
単離の前段階として得られる情報が TLC の発色試薬あるいは HPLC などの UV
スペクトルにのみに依存し, 対象としている化合物が既知か未知かの判断ができないためである …
スペクトルにのみに依存し, 対象としている化合物が既知か未知かの判断ができないためである …