Regulator of G-protein signaling 18 controls both platelet generation and function
N Delesque-Touchard, C Pendaries, C Volle-Challier… - PloS one, 2014 - journals.plos.org
RGS18 is a myeloerythroid lineage-specific regulator of G-protein signaling, highly
expressed in megakaryocytes (MKs) and platelets. In the present study, we describe the first …
expressed in megakaryocytes (MKs) and platelets. In the present study, we describe the first …
Systems biology of megakaryocytes
A Kaushansky, K Kaushansky - A Systems Biology Approach to Blood, 2014 - Springer
The molecular pathways that regulate megakaryocyte production have historically been
identified through multiple candidate gene approaches. Several transcription factors critical …
identified through multiple candidate gene approaches. Several transcription factors critical …
Polycythaemia‐inducing mutations in the erythropoietin receptor (EPOR): mechanism and function as elucidated by epidermal growth factor receptor–EPOR chimeras
M Gross, N Ben‐Califa, MF McMullin… - British journal of …, 2014 - Wiley Online Library
Primary familial and congenital polycythaemia (PFCP) is a disease characterized by
increased red blood cell mass, and can be associated with mutations in the intracellular …
increased red blood cell mass, and can be associated with mutations in the intracellular …
BCR-ABL negative myeloproliferative neoplasia: a review of involved molecular mechanisms.
SM Koopmans, HC Schouten… - Histology and …, 2014 - europepmc.org
The clonal bone marrow stem cell disorders essential thrombocythemia (ET), polycythemia
vera (PV) and primary myelofibrosis (PMF) belong to the group of Philadelphia chromosome …
vera (PV) and primary myelofibrosis (PMF) belong to the group of Philadelphia chromosome …