[HTML][HTML] How acceptable are antiretrovirals for the prevention of sexually transmitted HIV?: A review of research on the acceptability of oral pre-exposure prophylaxis …
Recent research has demonstrated how antiretrovirals (ARVs) could be effective in the
prevention of sexually transmitted HIV. We review research on the acceptability of oral pre …
prevention of sexually transmitted HIV. We review research on the acceptability of oral pre …
Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study
RM Grant, PL Anderson, V McMahan, A Liu… - The Lancet infectious …, 2014 - thelancet.com
Background The effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake,
adherence, and sexual practices. We aimed to assess these factors in a cohort of HIV …
adherence, and sexual practices. We aimed to assess these factors in a cohort of HIV …
[HTML][HTML] HIV protective efficacy and correlates of tenofovir blood concentrations in a clinical trial of PrEP for HIV prevention
Background: Antiretroviral pre-exposure prophylaxis (PrEP) is a novel HIV prevention
strategy for which adherence is a known determinant of efficacy. Blood concentrations of …
strategy for which adherence is a known determinant of efficacy. Blood concentrations of …
[HTML][HTML] FEM-PrEP: adherence patterns and factors associated with adherence to a daily oral study product for pre-exposure prophylaxis
AL Corneli, J Deese, M Wang, D Taylor… - JAIDS Journal of …, 2014 - journals.lww.com
Background: Several clinical trials have demonstrated the safety and effectiveness of oral
tenofovir disoproxil fumarate (TDF), with or without emtricitabine (FTC), as pre-exposure …
tenofovir disoproxil fumarate (TDF), with or without emtricitabine (FTC), as pre-exposure …
Syphilis predicts HIV incidence among men and transgender women who have sex with men in a preexposure prophylaxis trial
MM Solomon, KH Mayer, DV Glidden… - Clinical Infectious …, 2014 - academic.oup.com
Syphilis infection was associated with HIV incidence in an HIV-prevention trial that
randomized participants to once-daily emtricitabine/tenofovir (FTC/TDF) vs placebo …
randomized participants to once-daily emtricitabine/tenofovir (FTC/TDF) vs placebo …
Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection
TN Gengiah, A Moosa, A Naidoo… - International journal of …, 2014 - Springer
Background There are 34 million people living with human immunodeficiency virus (HIV)
worldwide and each year this number increases. Until a vaccine is discovered, the …
worldwide and each year this number increases. Until a vaccine is discovered, the …
Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus
CD Andrews, WR Spreen, H Mohri, L Moss, S Ford… - Science, 2014 - science.org
GSK1265744 (GSK744) is an integrase strand-transfer inhibitor that has been formulated as
a long-acting (LA) injectable suitable for monthly to quarterly clinical administration. GSK744 …
a long-acting (LA) injectable suitable for monthly to quarterly clinical administration. GSK744 …
[HTML][HTML] Changes in renal function associated with oral emtricitabine/tenofovir disoproxil fumarate use for HIV pre-exposure prophylaxis
MM Solomon, JR Lama, DV Glidden, K Mulligan… - Aids, 2014 - journals.lww.com
Objective: Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis decreases sexual
acquisition of HIV infection. We sought to evaluate the renal safety of TDF in HIV-uninfected …
acquisition of HIV infection. We sought to evaluate the renal safety of TDF in HIV-uninfected …
HIV pre-exposure prophylaxis in men who have sex with men and transgender women: a secondary analysis of a phase 3 randomised controlled efficacy trial
SP Buchbinder, DV Glidden, AY Liu… - The Lancet infectious …, 2014 - thelancet.com
Background For maximum effect pre-exposure prophylaxis should be targeted to the
subpopulations that account for the largest proportion of infections (population-attributable …
subpopulations that account for the largest proportion of infections (population-attributable …
HIV prevention in clinical care settings: 2014 recommendations of the International Antiviral Society–USA Panel
Importance Emerging data warrant the integration of biomedical and behavioral
recommendations for human immunodeficiency virus (HIV) prevention in clinical care …
recommendations for human immunodeficiency virus (HIV) prevention in clinical care …