The chromium-release assay developed in 1968 is still the most commonly used method to
measure cytotoxicity by T cells and by natural killer cells. Target cells are loaded in vitro with …

Gastric and colorectal cancers (GC and CRC) have poor prognosis and are resistant to
chemo-and/or radiotherapy. In the present study, the prophylactic effects of dendritic cell …

The promise of cell-based immunotherapies for the treatment of cancer offers the potential of
therapeutic synergy with chemo-and radiotherapies that may overcome current limitations …

Unresectable metastatic bone sarcoma and soft-tissue sarcomas (STS) are incurable due to
the inability to eradicate chemoresistant cancer stem–like cells (sCSC) that are likely …

Cytokine-induced killer (CIK) cells have shown cytolytic ability against ovarian cancer cells
in vitro and in vivo. This study was aimed to evaluate the clinical efficacy of maintenance …

CIK cells therapy has been evaluated as an adoptive cell immunotherapy for cancer
patients, but there still have not been any standardized systems for evaluating the antitumor …

Cord blood has gradually become an important source for hematopoietic stem cell
transplantation (HSCT) in the human, particularly in pediatric patients. Adoptive cellular …

Aims: To investigate the antitumor activity of cytokine-induced killer (CIK) cells combined
with epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) against gastric …

A method of obtaining expanded and activated natural killer (NK) cells with the phenotype
CD3− CD56+ and NK-like T cells with the phenotype CD3+ CD56+ comprises providing a …

Stimulating lymphocytes with Ifn-γ, anti-CD3, and interleukin-2 promotes the proliferation of
a cell population coexpressing T-lymphocyte surface antigens such as CD3, CD8a, and …