Addictions to licit and illicit drugs are chronic relapsing brain disorders that affect circuits that
regulate reward, motivation, memory, and decision-making. Drug-induced pathological …

A major development in drug addiction research in recent years has been the discovery that
immune signaling within the central nervous system contributes significantly to mesolimbic …

Methamphetamine is a widely abused illicit drug. Recent epidemiological studies showed
that methamphetamine increases the risk for developing Parkinson's disease (PD) in …

BackgroundMaladaptive decision-making is assumed to be a core feature of cocaine
addiction. Indeed, numerous studies have reported deficits in non-social decision-making …

Introduction Blast injury to brain, a hundred-year old problem with poorly characterized
neuropathology, has resurfaced as health concern in recent deployments in Iraq and …

Glia (including astrocytes, microglia, and oligodendrocytes), which constitute the majority of
cells in the brain, have many of the same receptors as neurons, secrete neurotransmitters …

The proper operation of the mammalian brain requires dynamic interactions between
neurones and glial cells. Various types of glial cells are susceptible to morpho-functional …

Considerable insight has been gained into the comorbid, interactive effects of HIV and drug
abuse in the brain using experimental models. This review, which considers opiates …

Neuropsychiatric disorders are one of the leading causes of disability worldwide and affect
the health of billions of people. Previous publications have demonstrated that …

Long interspersed element 1 (L1) is a retroelement constituting∼ 17% of the human
genome. A single human cell has 80–100 copies of L1 capable of retrotransposition (L1 …