Disorders of the skeleton are one of the most common causes of chronic pain and long‐term
physical disability in the world. Chronic skeletal pain is caused by a remarkably diverse …

The treatment and management of chronic pain is a major challenge for clinicians. Chronic
pain is often underdiagnosed and undertreated, and there is a lack of awareness of the …

Pontospinal noradrenergic neurons are thought to form part of a descending endogenous
analgesic system that exerts inhibitory influences on spinal nociception. Using optogenetic …

Abstract α 2-Adrenoceptors are widely distributed throughout the central nervous system
(CNS) and the systemic administration of α 2-agonists such as dexmedetomidine produces …

Animal studies have suggested that the cerebellum, in addition to its motor functions, also
has a role in pain processing and modulation, possibly because of its extensive connections …

Emotions suffuse our lives: a symphony of feeling-usually whispering and murmuring in
pianissimo but occasionally screaming and shouting in fortissimo crescendo-filling every …

The influence of sex has been neglected in clinical studies on pain and analgesia, with the
vast majority of research conducted exclusively in males. However, both preclinical and …

Respiration is a motor system essential for the survival of the individual and of the species.
Because of its vital significance, studies on respiration often assume that breathing takes …

We present an experimental investigation of a novel intervention paradigm targeting
attentional bias–Attention Feedback Awareness and Control Training (A-FACT). A-FACT is …

The new edition of Complete Psychology is the definitive undergraduate textbook. It not only
fits exactly with the very latest BPS curriculum and offers integrated web support for students …