Prodrug-based nanoparticulate drug delivery strategies for cancer therapy
C Luo, J Sun, B Sun, Z He - Trends in pharmacological sciences, 2014 - cell.com
Despite the rapid developments in nanotechnology and biomaterials, the efficient delivery of
chemotherapeutic agents is still challenging. Prodrug-based nanoassemblies have many …
chemotherapeutic agents is still challenging. Prodrug-based nanoassemblies have many …
Nanoemulsions in translational research—opportunities and challenges in targeted cancer therapy
Nanoemulsion dosage form serves as a vehicle for the delivery of active pharmaceutical
ingredients and has attracted great attention in drug delivery and pharmacotherapy. In …
ingredients and has attracted great attention in drug delivery and pharmacotherapy. In …
Combination of small molecule prodrug and nanodrug delivery: amphiphilic drug–drug conjugate for cancer therapy
All drugs for cancer therapy face several transportation barriers on their tortuous journey to
the action sites. To overcome these barriers, an effective drug delivery system for cancer …
the action sites. To overcome these barriers, an effective drug delivery system for cancer …
In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug
In vivo monitoring of the biodistribution and activation of prodrugs is urgently required. Near
infrared (NIR) fluorescence-active fluorophores with excellent photostability are preferable …
infrared (NIR) fluorescence-active fluorophores with excellent photostability are preferable …
[HTML][HTML] Multifunctional enveloped mesoporous silica nanoparticles for subcellular co-delivery of drug and therapeutic peptide
GF Luo, WH Chen, Y Liu, Q Lei, RX Zhuo, XZ Zhang - Scientific reports, 2014 - nature.com
A multifunctional enveloped nanodevice based on mesoporous silica nanoparticle (MSN)
was delicately designed for subcellular co-delivery of drug and therapeutic peptide to tumor …
was delicately designed for subcellular co-delivery of drug and therapeutic peptide to tumor …
Enhancing the efficiency of gold nanoparticles treatment of cancer by increasing their rate of endocytosis and cell accumulation using rifampicin
MRK Ali, SR Panikkanvalappil… - Journal of the American …, 2014 - ACS Publications
To minimize the toxicity of gold nanoparticles (AuNPs) in cancer treatment, we have
developed a technique, which utilizes lesser amount of AuNPs while exhibiting increased …
developed a technique, which utilizes lesser amount of AuNPs while exhibiting increased …
Multi-drug delivery system based on alginate/calcium carbonate hybrid nanoparticles for combination chemotherapy
JL Wu, CQ Wang, RX Zhuo, SX Cheng - Colloids and Surfaces B …, 2014 - Elsevier
A facile strategy to prepare nano-sized drug carriers for co-delivery of multiple types of drugs
in combination chemotherapy was developed. Inorganic/organic hybrid alginate/CaCO 3 …
in combination chemotherapy was developed. Inorganic/organic hybrid alginate/CaCO 3 …
Dual sensitive and temporally controlled camptothecin prodrug liposomes codelivery of siRNA for high efficiency tumor therapy
Y Li, R Liu, J Yang, G Ma, Z Zhang, X Zhang - Biomaterials, 2014 - Elsevier
The combination of chemotherapeutic drug camptothecin (CPT) and siPlk1 could prohibit
cancer development with combined effects. To ensure the two drugs could be …
cancer development with combined effects. To ensure the two drugs could be …
Tunable temperature-responsive supramolecular hydrogels formed by prodrugs as a codelivery system
W Ha, J Yu, X Song, J Chen, Y Shi - ACS Applied Materials & …, 2014 - ACS Publications
Taking advantage of the strong hydrophobicity of the anticancer drug camptothecin (CPT),
the CPT molecule was conjugated to a class of low-molecular-weight (MW) poly (ethylene …
the CPT molecule was conjugated to a class of low-molecular-weight (MW) poly (ethylene …
Folate-decorated and reduction-sensitive micelles assembled from amphiphilic polymer–camptothecin conjugates for intracellular drug delivery
C Liu, J Yuan, X Luo, M Chen, Z Chen… - Molecular …, 2014 - ACS Publications
It is one of the challenges for a wide clinical application of polymer micelles to address the
structure disintegration and premature drug release before reaching a pathological site. In …
structure disintegration and premature drug release before reaching a pathological site. In …