Calcium's role in mechanotransduction during muscle development

T Benavides Damm, M Egli - Cellular Physiology and Biochemistry, 2014 - karger.com
Mechanotransduction is a process where cells sense their surroundings and convert the
physical forces in their environment into an appropriate response. Calcium plays a crucial …

Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging

A Umanskaya, G Santulli, W Xie… - Proceedings of the …, 2014 - National Acad Sciences
Age-related skeletal muscle dysfunction is a leading cause of morbidity that affects up to half
the population aged 80 or greater. Here we tested the effects of increased mitochondrial …

Trimeric intracellular cation channels and sarcoplasmic/endoplasmic reticulum calcium homeostasis

X Zhou, P Lin, D Yamazaki, KH Park… - Circulation …, 2014 - Am Heart Assoc
Trimeric intracellular cation channels (TRIC) represents a novel class of trimeric intracellular
cation channels. Two TRIC isoforms have been identified in both the human and the mouse …

Automated detection and analysis of Ca2+ sparks in xy image stacks using a thresholding algorithm implemented within the open-source image analysis platform …

EM Steele, DS Steele - Biophysical journal, 2014 - cell.com
Previous studies have used analysis of Ca 2+ sparks extensively to investigate both normal
and pathological Ca 2+ regulation in cardiac myocytes. The great majority of these studies …

[HTML][HTML] Assessment of calcium sparks in intact skeletal muscle fibers

KH Park, N Weisleder, J Zhou, K Gumpper… - Journal of Visualized …, 2014 - ncbi.nlm.nih.gov
Maintaining homeostatic Ca 2+ signaling is a fundamental physiological process in living
cells. Ca 2+ sparks are the elementary units of Ca 2+ signaling in the striated muscle fibers …

Myofibrillar misalignment correlated to triad disappearance of mdx mouse gastrocnemius muscle probed by SHG microscopy

D Rouède, P Coumailleau, E Schaub… - Biomedical optics …, 2014 - opg.optica.org
We show that the canonical single frequency sarcomeric SHG intensity pattern (SHG-IP) of
control muscles is converted to double frequency sarcomeric SHG-IP in preserved mdx …

Monovalent cationic channel activity in the inner membrane of nuclei from skeletal muscle fibers

V Yarotskyy, RT Dirksen - Biophysical Journal, 2014 - cell.com
Nuclear ion channels remain among the least studied and biophysically characterized
channels. Although considerable progress has been made in characterizing calcium release …

A mitochondrial perspective on striated muscle physiopathology: insights from sepsis, denervation, and dystrophinopathies

R Godin - 2014 - papyrus.bib.umontreal.ca
Mitochondria are increasingly being recognized for their role in contributing in cellular
damage. Mitochondrial dysfunctions, in addition to causing energy failure, contribute to …

[图书][B] Sodium dysregulation coupled with calcium entry leads to muscular dystrophy in mice

AR Burr - 2014 - search.proquest.com
Abstract Duchenne Muscular Dystrophy (DMD) and many of the limb girdle muscular
dystrophies form a family of diseases called sarcoglycanopathies. In these diseases …