Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

SUMMARY A vast and diverse array of microbial species displaying great phylogenic,
genomic, and metabolic diversity have colonized the gastrointestinal tract. Resident …

Activators of innate immunity may have the potential to combat a broad range of infectious
agents. We report that treatment with bacterial flagellin prevented rotavirus (RV) infection in …

Background. Rotavirus causes 500 000 deaths and millions of physician visits and
hospitalizations per year, with worse outcomes and reduced vaccine efficacy in developing …

Molecular methods such as real-time polymerase chain reaction (PCR) are rapidly replacing
traditional tests to detect fecal viral pathogens in childhood diarrhea. This technique has …

Vaccination is one of the most successful applications of immunology and for a long time
has depended on parenteral administration protocols. However, recent studies have pointed …

Background Previous findings suggested that Lactobacillus rhamnosus CRL1505 is able to
increase resistance of children to intestinal viral infections. However, the intestinal cells …

Rotavirus (RV) replicates efficiently in intestinal epithelial cells (IECs) in vivo despite the
activation of a local host interferon (IFN) response. Previously, we demonstrated that …

Background Rotavirus is the most common cause of severe secretory diarrhoea in infants
and young children globally. The rotaviral enterotoxin, NSP4, has been proposed to …

Mutualism with our intestinal microbiota is a prerequisite for healthy existence. This requires
physical separation of the majority of the microbiota from the host (by secreted …