The survival and colonization of tumor cells at new locations involve a variety of complex
genetic, epigenetic, and microenvironmental factors. TRIM24 was originally named …

Background: The Japanese 'BALAD'model offers the first objective, biomarker-based, tool for
assessment of prognosis in hepatocellular carcinoma, but relies on dichotomisation of the …

Glycinamide ribonucleotide transformylase (GART) is a folate-dependent enzyme in the de
novo purine pathway that has been the target of antineoplastic intervention for almost 2 …

Background p21-activated protein kinase (PAK) 6 is a serine-threonine kinase belonging to
the PAK family. Previous studies have indicated that abnormal expressions of PAK1, PAK2 …

Natural killer (NK) cells are important effector cells for the first line of defense against tumor.
Distant MHC class I homolog MICA has been identified as human ligand for NK cell …

Background Human hepatocellular carcinoma (HCC) is one of the most common fatal
cancers and an important health problem worldwide, but its mechanism is still unclear …

Despite major advancements in the clinical management of hepatocellular carcinoma
(HCC), the natural history of this disease is characterized by an invariably poor prognosis …

Vasohibin 1, an endothelium-derived negative feedback regulator of angiogenesis, is
induced by fibroblast growth factor 2 (FGF-2) and vascular endothelial growth factor A …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death in the world.
The gene glypican-3 (GPC3) is reported to be a potential therapeutic target for HCC. In this …

GPR37, also known as parkin-associated endothelin-like receptor (Pael-R), is an orphan G
protein-coupled receptor (GPCR). It has been reported that GPCRs play vital roles in the …