CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics‐guided clinical trials
EM Peñas‐LLedó, A LLerena - British journal of clinical …, 2014 - Wiley Online Library
Individual and population differences in polymorphic cytochrome P 450 enzyme function
have been known for decades. The biological significance of these differences has now …
have been known for decades. The biological significance of these differences has now …
Combination treatment of tamoxifen with risperidone in breast cancer
Tamoxifen has long been used and still is the most commonly used endocrine therapy for
treatment of both early and advanced estrogen receptor-positive breast cancer in pre-and …
treatment of both early and advanced estrogen receptor-positive breast cancer in pre-and …
CYP2D6 gene polymorphisms and predicted phenotypes in eight indigenous groups from northwestern Mexico
BP Lazalde-Ramos, ML Martínez-Fierro… - …, 2014 - Taylor & Francis
Aim: Polymorphisms in CYP2D6 impact the interindividual and interethnic variability of drug
efficiency; therefore, we determined the CYP2D6 allele distribution in eight Amerindian …
efficiency; therefore, we determined the CYP2D6 allele distribution in eight Amerindian …
Liver enzyme abnormalities during antipsychotic treatment: a case report of risperidone-associated hepatotoxicity
E López-Torres, Á Süveges… - Drug metabolism and …, 2014 - degruyter.com
Background: Drug-induced liver enzyme abnormalities may indicate hepatic injury.
Antipsychotic drugs also may cause increase in the liver enzymes and serum bilirubin …
Antipsychotic drugs also may cause increase in the liver enzymes and serum bilirubin …
Pharmacogenetic aspects of the activity of cytochromes P450 in the metabolism of antipsychotics
OO Fursa, VL Kozlovskiĭ - Zhurnal Nevrologii i Psikhiatrii Imeni SS …, 2014 - europepmc.org
Pharmacogenetic tests that allow the clinician to individualize dosage to the patient
according to the activity of their metabolism are described. Pharmacogenetic aspects of the …
according to the activity of their metabolism are described. Pharmacogenetic aspects of the …
[PDF][PDF] A case report of an ultra-rapid metabolizer on depot formulations of risperidone and haloperidol and reflections on metabolic pathways
H Koch, H Zellmer… - Acta medica Medianae, 2014 - publisher.medfak.ni.ac.rs
The treatment of chronic schizophrenia with prominent negative symptoms poses a
formidable challenge for both patients and psychiatrists as well as their relatives (1-3) …
formidable challenge for both patients and psychiatrists as well as their relatives (1-3) …
Multiple Kernel Learning for Gene Prioritization, Clustering, and Functional Enrichment Analysis
DH Millis - 2014 - search.proquest.com
Gene prioritization is the process of ranking a list of candidate genes such that the genes
that are most likely involved in a biological process of interest receive the highest rankings …
that are most likely involved in a biological process of interest receive the highest rankings …