Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies
M Maccarrone, M Guzmán, K Mackie… - Nature Reviews …, 2014 - nature.com
Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …
important roles in neuronal and glial development. Recent experimental evidence suggests …
Aging in the olfactory system
AS Mobley, DJ Rodriguez-Gil, F Imamura… - Trends in …, 2014 - cell.com
With advancing age, the ability of humans to detect and discriminate odors declines. In light
of the rapid progress in analyzing molecular and structural correlates of developing and …
of the rapid progress in analyzing molecular and structural correlates of developing and …
Miswiring the brain: Δ9‐tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin‐2 degradation pathway
G Tortoriello, CV Morris, A Alpar, J Fuzik… - The EMBO …, 2014 - embopress.org
Children exposed in utero to cannabis present permanent neurobehavioral and cognitive
impairments. Psychoactive constituents from Cannabis spp., particularly Δ9 …
impairments. Psychoactive constituents from Cannabis spp., particularly Δ9 …
Cannabinoid-induced actomyosin contractility shapes neuronal morphology and growth
Endocannabinoids are recently recognized regulators of brain development, but molecular
effectors downstream of type-1 cannabinoid receptor (CB1R)-activation remain incompletely …
effectors downstream of type-1 cannabinoid receptor (CB1R)-activation remain incompletely …
The cannabinoid CB2 receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis
HK Avraham, S Jiang, Y Fu… - British journal of …, 2014 - Wiley Online Library
Background and Purpose HIV‐1 glycoprotein G p120 induces apoptosis in rodent and
human neurons in vitro and in vivo. HIV‐1/G p120 is involved in the pathogenesis of HIV …
human neurons in vitro and in vivo. HIV‐1/G p120 is involved in the pathogenesis of HIV …
Functions of the CB1 and CB2 Receptors in Neuroprotection at the Level of the Blood–Brain Barrier
E Vendel, ECM de Lange - Neuromolecular medicine, 2014 - Springer
The cannabinoid (CB) receptors are the main targets of the cannabinoids, which include
plant cannabinoids, endocannabinoids and synthetic cannabinoids. Over the last few years …
plant cannabinoids, endocannabinoids and synthetic cannabinoids. Over the last few years …
Pharmacological blockade of either cannabinoid CB1 or CB2 receptors prevents both cocaine-induced conditioned locomotion and cocaine-induced reduction of …
E Blanco-Calvo, P Rivera, S Arrabal… - Frontiers in integrative …, 2014 - frontiersin.org
Addiction to major drugs of abuse, such as cocaine, has recently been linked to alterations
in adult neurogenesis in the hippocampus. The endogenous cannabinoid system modulates …
in adult neurogenesis in the hippocampus. The endogenous cannabinoid system modulates …
Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting
There is clear evidence on the neuroprotective role of the endocannabinoid (eCB) signaling
cascade in various models of epilepsy. In particular, increased levels of eCBs protect …
cascade in various models of epilepsy. In particular, increased levels of eCBs protect …
Extracellular signals controlling neuroblast migration in the postnatal brain
G Lalli - Cellular and Molecular Control of Neuronal Migration, 2014 - Springer
The most prominent example of long-distance migration in the postnatal brain is the rostral
migratory stream (RMS) formed by neuroblasts originating in the subventricular zone (SVZ) …
migratory stream (RMS) formed by neuroblasts originating in the subventricular zone (SVZ) …
Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?
Neural stem cells (NSCs) from the subventricular zone (SVZ) have been indicated as a
source of new oligodendrocytes to use in regenerative medicine for myelin pathologies …
source of new oligodendrocytes to use in regenerative medicine for myelin pathologies …