The AMP-activated protein kinase (AMPK) is a sensor of cellular energy and nutrient status,
expressed almost universally in eukaryotes as heterotrimeric complexes comprising catalytic …

Type 2 diabetes (T2D) is a metabolic disease characterized by insulin resistance, β-cell
dysfunction, and elevated hepatic glucose output. Over 350 million people worldwide have …

The AMP‐activated protein kinase (AMPK) is a sensor of cellular energy status that
regulates cellular and whole‐body energy balance. A recently reported crystal structure has …

The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signaling pathway
arose early during evolution of eukaryotic cells, when it appears to have been involved in …

The SNF1 (sucrose non-fermenting 1)-related protein kinases 1 (SnRKs1) are the plant
orthologs of the budding yeast SNF1 and mammalian AMPK (AMP-activated protein kinase) …

In the developing and mature brain, mitochondria act as central hubs for distinct but
interwined pathways, necessary for neural development, survival, activity, connectivity and …

AMP-activated protein kinase (AMPK) is an important energy sensor that may be critical in
regulating renal lipid accumulation. To evaluate the role of AMPK in mediating renal lipid …

AMP-activated protein kinase (AMPK), an established metabolic stress sensor, has gained
popularity in cancer biology due to its ability to control cellular growth and mediate cell cycle …

Aims/hypothesis Obesity is characterised by lipid accumulation in skeletal muscle, which
increases the risk of developing insulin resistance and type 2 diabetes. AMP-activated …

The oxidative phosphorylation (OXPHOS) system in mitochondria is responsible for the
generation of the majority of cellular energy in the form of ATP. Patients with genetic …