The Molecular Balancing Act of p16INK4a in Cancer and Aging
KM LaPak, CE Burd - Molecular Cancer Research, 2014 - AACR
Abstract p16INK4a, located on chromosome 9p21. 3, is lost among a cluster of neighboring
tumor suppressor genes. Although it is classically known for its capacity to inhibit cyclin …
tumor suppressor genes. Although it is classically known for its capacity to inhibit cyclin …
Physiological networks and disease functions of RNA‐binding protein AUF1
AE Moore, DM Chenette, LC Larkin… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
Regulated messenger RNA (mRNA) decay is an essential mechanism that governs proper
control of gene expression. In fact, many of the most physiologically potent proteins are …
control of gene expression. In fact, many of the most physiologically potent proteins are …
The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1
SF Hendrayani, HH Al-Khalaf… - Journal of Biological …, 2014 - ASBMB
The development and spread of mammary carcinomas require synergetic interplay between
tumor cells and their microenvironment through paracrine secretions, which are still not well …
tumor cells and their microenvironment through paracrine secretions, which are still not well …
MicroRNA-141 and microRNA-146b-5p inhibit the prometastatic mesenchymal characteristics through the RNA-binding protein AUF1 targeting the transcription factor …
HH Al-Khalaf, A Aboussekhra - Journal of Biological Chemistry, 2014 - ASBMB
miR-141 and miR-146b-5p are two important tumor suppressor microRNAs, which control
several cancer-related genes and processes. In the present report, we have shown that …
several cancer-related genes and processes. In the present report, we have shown that …
5-Azacytidine enhances the radiosensitivity of CNE2 and SUNE1 cells in vitro and in vivo possibly by altering DNA methylation
W Jiang, YQ Li, N Liu, Y Sun, QM He, N Jiang, YF Xu… - PLoS …, 2014 - journals.plos.org
The radioresistance of tumor cells remains a major cause of treatment failure in
nasopharyngeal carcinoma (NPC). Recently, several reports have highlighted the …
nasopharyngeal carcinoma (NPC). Recently, several reports have highlighted the …
Effect of Sox2 on proliferation of cervical squamous cancer cell line SiHa
JI Jing, N Fen-ru, LIU Hai-juan - Journal of Sichuan University …, 2014 - jsu-mse.com
To investigate the effect and its mechanism of stem cell related transcription factor Sox2 on
the proliferation of cervical squamous carcinoma cell line SiHa. Methods Plasmid pIRES …
the proliferation of cervical squamous carcinoma cell line SiHa. Methods Plasmid pIRES …
Sox2 对宫颈鳞癌细胞增殖能力影响的研究
冀静， 宁芬茹， 刘海娟 - 四川大学学报(医学版), 2014 - ykxb.scu.edu.cn
目的探讨干细胞转录因子Sox2 对宫颈鳞癌细胞增殖能力的影响及其机制. 方法将质粒pIRES-
EGFP-Sox2 转染宫颈鳞癌SiHa 细胞系, 采用G418 筛选构建稳定表达Sox2 的SiHa …
EGFP-Sox2 转染宫颈鳞癌SiHa 细胞系, 采用G418 筛选构建稳定表达Sox2 的SiHa …
[引用][C] Identification and Characterization of Au-Rich Elements and Trans-Acting Factors Involved in the Posttranscriptional Regulation of Human Interleukin-3
JA González Feliciano, CIC González Vargas - 2014