Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the
inner leaflet of the plasma membrane in neural tissues. PS is synthesized from …

Nature provides an enormous diversity of lipid molecules that originate from various
pathways. To gain insight into the metabolism and dynamics of lipid species, the application …

The modulatory role of choline on the fetal epigenome and the impact of in utero choline
supply on fetal programming and health are of great interest. Studies in animals and/or …

Milk and dairy products are an important source of choline, a nutrient essential for human
health. Infant formula derived from bovine milk contains a number of metabolic forms of …

Mass spectrometry is an ideal tool for investigations of the metabolome in human plasma. To
investigate the impact of smoking on the human metabolome, we performed an untargeted …

We have reported that folic acid, vitamin B12, and omega‐3 fatty acids are interlinked in the
one carbon cycle and have implications for fetal programming. Our earlier studies …

Introduction: The consequences of wide spread vegetarianism due to low vitamin B 12 on
brain development and functioning is gaining importance. However, there are no studies …

Background During fetal development, docosahexaenoic (DHA) and arachidonic acid (ARA)
are particularly enriched in brain phospholipids. After preterm delivery, fetal enrichment of …

Maternal choline supplementation (MCS) induces lifelong cognitive benefits in the Ts65Dn
mouse, a trisomic mouse model of Down syndrome and Alzheimer's disease. To gain insight …

The role of lipids in human health and disease is taking the center stage. In the last decades,
there has been an intense effort to develop suitable methodologies to discover, identify, and …