A current understanding of vascular calcification in CKD

NJ Paloian, CM Giachelli - American Journal of Physiology …, 2014 - journals.physiology.org
Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have
significant cardiovascular morbidity and mortality that is in part due to the development of …

Basic mechanisms of calcific aortic valve disease

P Mathieu, MC Boulanger - Canadian Journal of Cardiology, 2014 - Elsevier
Calcific aortic valve disease (CAVD) is the most common heart valve disorder. There is no
medical treatment to prevent and/or promote the regression of CAVD. Hence, it is of foremost …

Reprogramming the specificity of sortase enzymes

BM Dorr, HO Ham, C An… - Proceedings of the …, 2014 - National Acad Sciences
Staphylococcus aureus sortase A catalyzes the transpeptidation of an LPXTG peptide
acceptor and a glycine-linked peptide donor and has proven to be a powerful tool for site …

[HTML][HTML] One-step antibody immobilization-based rapid and highly-sensitive sandwich ELISA procedure for potential in vitro diagnostics

SK Vashist, E Marion Schneider, E Lam, S Hrapovic… - Scientific reports, 2014 - nature.com
An improved enzyme-linked immunosorbent (ELISA) assay using one-step antibody
immobilization has been developed for the detection of human fetuin A (HFA), a specific …

Vascular calcification and renal bone disorders

KC Lu, CC Wu, JF Yen, WC Liu - The Scientific World Journal, 2014 - Wiley Online Library
At the early stage of chronic kidney disease (CKD), the systemic mineral metabolism and
bone composition start to change. This alteration is known as chronic kidney disease …

Biomarkers of vascular calcification and mortality in patients with ESRD

JJ Scialla, WHL Kao, C Crainiceanu… - Clinical Journal of the …, 2014 - journals.lww.com
Biomarkers of Vascular Calcification and Mortality in Patien... : Clinical Journal of the
American Society of Nephrology Biomarkers of Vascular Calcification and Mortality in …

Vitamin K1 to slow vascular calcification in haemodialysis patients (VitaVasK trial): a rationale and study protocol

T Krueger, G Schlieper, L Schurgers… - Nephrology Dialysis …, 2014 - academic.oup.com
Background Patients on haemodialysis (HD) exhibit increased cardiovascular mortality
associated with accelerated vascular calcification (VC). VC is influenced by inhibitors such …

Vascular calcification in chronic kidney disease: are biomarkers useful for probing the pathobiology and the health risks of this process in the clinical scenario?

S Liabeuf, H Okazaki, L Desjardins… - Nephrology Dialysis …, 2014 - academic.oup.com
Patients with chronic kidney disease (CKD) are at a particularly high risk for cardiovascular
disease. Vascular calcification (VC) is considered a cardiovascular risk marker, so in CKD …

[HTML][HTML] Fetuin-A and albumin alter cytotoxic effects of calcium phosphate nanoparticles on human vascular smooth muscle cells

Y Dautova, D Kozlova, JN Skepper, M Epple… - PloS one, 2014 - journals.plos.org
Calcification is a detrimental process in vascular ageing and in diseases such as
atherosclerosis and arthritis. In particular, small calcium phosphate (CaP) crystal deposits …

Proinflammatory and antiinflammatory attributes of fetu Iν-A: a novel hepatokine modulating cardiovascular and glycemic outcomes in metabolic syndrome

S Mukhopadhyay, SA Mondal, M Kumar, D Dutta - Endocrine practice, 2014 - Elsevier
Objective Fetuin-A is a novel hepatokine. The number of biologic roles attributed to fetuin-A
has increased exponentially in the past decade. The objective of this review is to discuss the …