Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study

C Jacobsen, J Hagemeier, KM Myhr… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objectives To identify MRI biomarkers associated with long-term disability progression in
patients with multiple sclerosis (MS), and to define the rate of evolution of global, tissue …

Multiple sclerosis: altered thalamic resting-state functional connectivity and its effect on cognitive function

F Tona, N Petsas, E Sbardella, L Prosperini… - Radiology, 2014 - pubs.rsna.org
Purpose To investigate, by using resting-state (RS) functional magnetic resonance (MR)
imaging, thalamocortical functional connectivity (FC) and its correlations with cognitive …

Associations between proprioceptive neural pathway structural connectivity and balance in people with multiple sclerosis

BW Fling, GG Dutta, H Schlueter… - Frontiers in human …, 2014 - frontiersin.org
Mobility and balance impairments are a hallmark of multiple sclerosis (MS), affecting nearly
half of patients at presentation and resulting in decreased activity and participation, falls …

[HTML][HTML] Jacobian integration method increases the statistical power to measure gray matter atrophy in multiple sclerosis

K Nakamura, N Guizard, VS Fonov, S Narayanan… - NeuroImage: Clinical, 2014 - Elsevier
Gray matter atrophy provides important insights into neurodegeneration in multiple sclerosis
(MS) and can be used as a marker of neuroprotection in clinical trials. Jacobian integration …

Insights from magnetic resonance imaging

M Filippi, A Charil, M Rovaris, M Absinta… - Handbook of clinical …, 2014 - Elsevier
Recent years have witnessed impressive advancements in the use of magnetic resonance
imaging (MRI) for the assessment of patients with multiple sclerosis (MS). Complementary to …

MRI evaluation of grey matter atrophy and disease course in multiple sclerosis: an overview of current knowledge

CO Jacobsen, E Farbu - Acta Neurologica Scandinavica, 2014 - Wiley Online Library
Multiple sclerosis (MS) is characterized by chronic inflammation of the central nervous
system, and magnetic resonance imaging (MRI) is used as both a diagnostic tool and a …

Thalamic atrophy and cognitive impairment in clinically isolated syndrome and multiple sclerosis

T Štecková, P Hluštík, V Sládková, F Odstrčil… - Journal of the …, 2014 - Elsevier
Background Cognitive deficits worsen the quality of life in multiple sclerosis and may be
predicted by deep gray matter atrophy, especially thalamic atrophy. This relationship has not …

Longitudinal MRI and neuropsychological assessment of patients with clinically isolated syndrome

T Uher, J Blahova-Dusankova, D Horakova… - Journal of …, 2014 - Springer
Cognitive impairment (CI) may occur in clinically isolated syndrome (CIS) patients. While the
relationship between CI and magnetic resonance imaging (MRI) has been investigated …

The clinical impact of cerebellar grey matter pathology in multiple sclerosis

A Damasceno, BP Damasceno, F Cendes - PLoS One, 2014 - journals.plos.org
Background The cerebellum is an important site for cortical demyelination in multiple
sclerosis, but the functional significance of this finding is not fully understood. Objective To …

[HTML][HTML] MRI correlates of disability progression in patients with CIS over 48 months

T Uher, D Horakova, N Bergsland, M Tyblova… - NeuroImage: Clinical, 2014 - Elsevier
Background Gray matter (GM) and white matter (WM) pathology has an important role in
disease progression of multiple sclerosis (MS). Objectives To investigate the association …