Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review

V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …

Role of exercise-induced reactive oxygen species in the modulation of heat shock protein response

S Fittipaldi, I Dimauro, N Mercatelli… - Free radical …, 2014 - Taylor & Francis
The multiple roles that have been associated with heat shock proteins (HSPs), inside and
outside cells are remarkable. HSPs have been found to play a fundamental role in multiple …

[6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling

EK Radhakrishnan, SV Bava, SS Narayanan, LR Nath… - PloS one, 2014 - journals.plos.org
We report mechanism-based evidence for the anticancer and chemopreventive efficacy of
[6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in …

Structure-based lead discovery for protein kinase C zeta inhibitor design by exploiting kinase–inhibitor complex crystal structure data and potential therapeutics for …

QC Shao, CJ Zhang, J Li - Archives of pharmacal research, 2014 - Springer
The protein kinase C (PKC) is a family of serine/threonine kinases with a broad range of
cellular targets. Members of the PKC family participate at the diverse biological events …

Endocytic and NBT-reduction activities and TNF expression by macrophages and monocytes of the armadillo (Dasypus novemcinctus)

MR Escobedo-Guerra, D Haro-Cruz… - Iranian Journal of …, 2014 - journals.shirazu.ac.ir
The armadillo could be considered as an experimental model for leprosy studies.
Mycobacterium leprae main host cells are macrophages and Schwann cells. However …

[PDF][PDF] Gingerol Induces Caspase-Dependent Apoptosis and Prevents

EK Radhakrishnan, SV Bava, SS Narayanan, LR Nath… - 2014 - academia.edu
We report mechanism-based evidence for the anticancer and chemopreventive efficacy of
[6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in …

Pharmaceutical compositions and related methods

L Braiman-Wiksman, T Tennenbaum… - US Patent App. 13 …, 2014 - Google Patents
The present disclosure relates to compositions and methods for accelerating the healing
process of wounds, increasing the closure of skin wounds, and decreasing inflammation at …

فعالیت اندوسیتی و احیاء NBT و بیان TNF به وسیله ماکروفاژها و مونوسیت‌های آرمادیلو (Dasypus novemcinctus)

مارکوس رامسس اسکوبدو-گواِرا, مارکوس رامسس… - مجله تحقیقات …, 2014‎ - ijvr.shirazu.ac.ir
آرمادیلو به عنوان یک مدل تجربی مناسب برای مطالعه جذام در نظر گرفته می‌شود. سلول‌های میزبان
اصلی میکوباکتریوم لپره‌آ، ماکروفاژها و سلول شوان می‌باشند. با این حال، فعالیت اندوسیتوز و …