Interactions between the intestinal microbiome and liver diseases

B Schnabl, DA Brenner - Gastroenterology, 2014 - Elsevier
The human intestine harbors a diverse community of microbes that promote metabolism and
digestion in their symbiotic relationship with the host. Disturbance of its homeostasis can …

[HTML][HTML] Pathological bacterial translocation in liver cirrhosis

R Wiest, M Lawson, M Geuking - Journal of hepatology, 2014 - Elsevier
Humans harbor nearly 100 trillion intestinal bacteria, which in terms of numbers, represents
around ten times more microbial cells than eukaryotic cells. The gastrointestinal (GI) tract …

Alterations of the human gut microbiome in liver cirrhosis

N Qin, F Yang, A Li, E Prifti, Y Chen, L Shao, J Guo… - Nature, 2014 - nature.com
Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent
worldwide. Here we characterize the gut microbiome in liver cirrhosis by comparing 98 …

Altered profile of human gut microbiome is associated with cirrhosis and its complications

JS Bajaj, DM Heuman, PB Hylemon, AJ Sanyal… - Journal of …, 2014 - Elsevier
Background & Aims The gut microbiome is altered in cirrhosis; however its evolution with
disease progression is only partly understood. We aimed to study changes in the …

[HTML][HTML] Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013

R Jalan, J Fernandez, R Wiest, B Schnabl… - Journal of …, 2014 - Elsevier
Bacterial infections are very common and represent one of the most important reasons of
progression of liver failure, development of liver-related complications, and mortality in …

Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis

JS Bajaj, DM Heuman, PB Hylemon… - Alimentary …, 2014 - Wiley Online Library
Background Safety of individual probiotic strains approved under Investigational New Drug
(IND) policies in cirrhosis with minimal hepatic encephalopathy (MHE) is not clear. Aim The …

[HTML][HTML] Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease

L Chen, W Wang, R Zhou, SC Ng, J Li, M Huang… - Medicine, 2014 - journals.lww.com
The intestinal microbiota plays an important role in the pathogenesis of inflammatory bowel
disease (IBD), and geographical and genetic backgrounds impact the composition of the …

[HTML][HTML] Microbiota and the gut-liver axis: bacterial translocation, inflammation and infection in cirrhosis

V Giannelli, V Di Gregorio, V Iebba… - World journal of …, 2014 - ncbi.nlm.nih.gov
Liver disease is associated with qualitative and quantitative changes in the intestinal
microbiota. In cirrhotic patients the alteration in gut microbiota is characterized by an …

The role of microbiota in hepatic encephalopathy

JS Bajaj - Gut microbes, 2014 - Taylor & Francis
Hepatic encephalopathy (HE), which consists of minimal (MHE) and overt (OHE) stages, is a
model for impaired gut-liver-brain axis in cirrhosis. Microbiota changes in both stages have …

[PDF][PDF] 肠道菌群影响宿主行为的研究进展

罗佳, 金锋 - 科学通报, 2014 - researchgate.net
摘要肠道内定植了数量众多, 种类丰富的肠道菌群, 它们和宿主间形成了互利共生的关系,
对宿主的健康产生着重大影响. 近年来, 随着对肠道菌群调控作用研究的不断深入 …