MC 1R, the c AMP pathway, and the response to solar UV: Extending the horizon beyond pigmentation

JC García‐Borrón, Z Abdel‐Malek… - Pigment cell & …, 2014 - Wiley Online Library
The melanocortin 1 receptor (MC 1R) is a G protein‐coupled receptor crucial for the
regulation of melanocyte proliferation and function. Upon binding melanocortins, MC 1R …

Growth inhibitory effects of large subunit ribosomal proteins in melanoma

GR Kardos, MS Dai… - Pigment cell & melanoma …, 2014 - Wiley Online Library
Ribosome biogenesis can modulate protein synthesis, a process heavily relied upon for
cancer cell proliferation. In this study, involvement of large subunit ribosomal proteins (RPL …

[PDF][PDF] Oncogene-induced senescence and the role of p53 in BRAFV600E melanoma

S Tran - 2014 - core.ac.uk
The p53 tumor suppressor has a critical role in maintaining the integrity of the genome and
loss-of-function p53 alterations are common in human tumours. In melanoma, p53 mutations …

Endothelin-1 Protects Human Melanocytes from the Photodamaging Effects of Ultraviolet Radiation by Activating the MAP Kinases JNK and p38

AM von Koschembahr - 2014 - search.proquest.com
Melanoma, the deadliest form of skin cancer, is derived from the malignant transformation of
melanocytes, epidermal cells that produce the pigment melanin. The main etiological factor …

[引用][C] Молекулярно-генетические особенности загара

Б Гилхрест - Косметика и медицина, 2014 - elibrary.ru