Significance: Innate and adaptive immunity play fundamental roles in the development of
hypertension and its complications. As effectors of the cell-mediated immune response …

The discovery of endothelin (ET) in 1988 has led to considerable effort to unravel its
implication in health and disease and the mechanisms evoked by ET. ET-1 and related …

Abstract Objective Homocysteine (Hcy) is known as an independent risk factor for
atherosclerosis. C-reactive protein (CRP) directly participates in initiation and progression of …

Atherosclerosis is a chronic inflammatory disease in the vessel, and inflammatory cytokines
play an important role in the inflammatory process of atherosclerosis. A high level of free …

АКТУАЛЬНАЯ ПРОБЛЕМА воздействия на бронхи и легкие экзогенных повреждающих
агентов и, в частности, табачного дыма. Так, согласно нашим морфологическим …

Inflammation is important for the initiation and the maintenance of vascular remodeling in
most of the animal models of pulmonary arterial hypertension (PAH), and therapeutic …

Through pattern recognition receptors, infections and tissue injuries drive innate immune
cells to trigger inflammation with elevated cytokines, chemokines, growth factors, and other …

OBJECTIVE African Americans (AAs) and Hispanics have higher diabetes and end-stage
renal disease but similar or lower early chronic kidney disease (CKD) compared with whites …

Heart failure (HF) is a complex heterogeneous syndrome with immune, metabolic and
neurohumoral mechanisms interacting and leading to gradual heart contractility impairment …

C‐reactive protein (CRP) performs two recognition functions that are relevant to
cardiovascular disease. First, in its native pentameric conformation, CRP recognizes …