[HTML][HTML] Competing endogenous RNAs (ceRNAs): new entrants to the intricacies of gene regulation

RV Kartha, S Subramanian - Frontiers in genetics, 2014 - frontiersin.org
The discovery of microRNAs (miRNAs) has led to a paradigm shift in our basic
understanding of gene regulation. Competing endogenous RNAs (ceRNAs) are the recent …

[HTML][HTML] A pathophysiological view of the long non-coding RNA world

F Di Gesualdo, S Capaccioli, M Lulli - Oncotarget, 2014 - ncbi.nlm.nih.gov
Because cells are constantly exposed to micro-environmental changes, they require the
ability to adapt to maintain a dynamic equilibrium. Proteins are considered critical for the …

Long non‐coding RNAs with low expression levels in cells are enriched in secreted exosomes

U Gezer, E Özgür, M Cetinkaya, M Isin… - Cell biology …, 2014 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) are involved in regulating chromatin modifications, gene
transcription, mRNA translation, and protein function. We recently reported a high variation …

A long non‐coding RNA, GAS5, plays a critical role in the regulation of miR‐21 during osteoarthritis

J Song, C Ahn, CH Chun, EJ Jin - Journal of orthopaedic …, 2014 - Wiley Online Library
ABSTRACT Growth Arrest‐Specific 5 (GAS5) is known to negatively regulate cell survival
and is aberrantly expressed in several cancers. The influence of GAS5 on osteoarthritis (OA) …

[HTML][HTML] Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis

Y He, Y Wu, C Huang, XM Meng, T Ma, BM Wu… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Long noncoding RNAs (lncRNAs) are being increasingly recognized as major players in
governing fundamental biological processes through diverse mechanisms. Maternally …

[HTML][HTML] Non-coding RNAs and gastric cancer

PF Li, SC Chen, T Xia, XM Jiang, YF Shao… - World journal of …, 2014 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) play key roles in development, proliferation, differentiation and
apoptosis. Altered ncRNA expression is associated with gastric cancer occurrence, invasion …

The decalog of long non-coding RNA involvement in cancer diagnosis and monitoring

T Kunej, J Obsteter, Z Pogacar, S Horvat… - Critical reviews in …, 2014 - Taylor & Francis
Long non-coding RNAs (lncRNAs) are transcripts without protein-coding capacity; initially
regarded as “transcriptional noise”, lately they have emerged as essential factors in both cell …

Analysis of lncRNA expression profiles in non-small cell lung cancers (NSCLC) and their clinical subtypes

J Yang, J Lin, T Liu, T Chen, S Pan, W Huang, S Li - Lung cancer, 2014 - Elsevier
Lung cancer is one of the most common human cancers worldwide. Among all lung cancer
cases, non-small cell lung cancer (NSCLC) accounts for approximately 85%. Long non …

Transcriptional and epigenetic regulation of T‐helper lineage specification

SK Tripathi, R Lahesmaa - Immunological reviews, 2014 - Wiley Online Library
Combined with TCR stimuli, extracellular cytokine signals initiate the differentiation of naive
CD 4+ T cells into specialized effector T‐helper (Th) and regulatory T (Treg) cell subsets …

[PDF][PDF] Roles of long non-coding RNAs on tumorigenesis and glioma development

JY Park, JE Lee, JB Park, H Yoo… - Brain tumor research …, 2014 - synapse.koreamed.org
More than 98% of eukaryotic transcriptomes are composed of non-coding RNAs with no
functional protein-coding capacity. Those transcripts also include tens of thousands of long …