Background: Studies in human as well as animal models indicate a gender-specific
responsiveness of the immune and organ systems with regard to shock, trauma, and sepsis …

Although reperfusion of an ischemic organ is essential to prevent irreversible tissue
damage, it may amplify tissue injury. This study investigates the role of endogenous …

A body of experimental evidence suggests that the female sex is associated with a lower risk
of mortality after trauma-hemorrhage. However, controversy remains regarding the …

Modern clinical management of the patients sustaining traumatic injuries and thermal burns
has resulted in their longer survival, but the clinical and pathological effects of these …

Altered immune response, including low-grade inflammatory processes, is involved in the
pathogenesis of schizophrenia, a chronic psychiatric disorder with complex etiology. Distinct …

Sexual dimorphisms exist in the incidence and severity of many diseases, with females
demonstrating relative protection from inflammatory conditions. The extent and mechanisms …

Castration induces antiapoptotic effect during myocardial regional ischemia reperfusion
Abstract Restoration of blood flow to Page 1 American Journal of BioMedicine 2014;2(3) …

Background Recent evidence supports the existence of a trauma induced secondary cardiac
injury (TISCI) that is associated with poor clinical outcome [1]. Cardiac dysfunction has been …

Autoimmune diseases (AD) are a heterogeneous group of 70 to 80 different inflammatory
disorders affecting approximately 3% to 8% of the population in developed countries. The …