Autoimmune myasthenia gravis (MG) is characterized by muscle weakness caused by
antibodies directed against proteins of the neuromuscular junction. The main antigenic …

Myasthenia Gravis (MG) is a paradigm of organ-specific autoimmune disease (AID). It is
mediated by antibodies that target the neuromuscular junction. The purpose of this review is …

To determine if patients with myasthenia gravis (MG) have antibodies to agrin, a
proteoglycan released by motor neurons and is critical for neuromuscular junction (NMJ) …

The neuromuscular junction (NMJ) is a synapse between motor neurons and skeletal
muscle fibers, and is critical for control of muscle contraction. Its formation requires neuronal …

Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas
involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4 …

Several studies have suggested that the autoantibodies (autoAbs) against muscle
acetylcholine receptor (AChR) of myasthenia gravis (MG) patients are the main pathogenic …

We examined the current evidence for the efficacy of IV immunoglobulin (IVIG) in
myasthenia gravis (MG) and the outcomes used to demonstrate this efficacy. There is class 1 …

The detection of low density lipoprotein-4 (LRP4) antibodies in double seronegative (dSN)
myasthenia gravis (MG) patients has provided new insights in the diagnosis and treatment of …

Muscle-specific tyrosine kinase (MuSK) autoantibody related myasthenia gravis (hereafter
MuSK-myasthenia gravis) is a life-threatening condition generally requiring complex …

To analyze the presence of autonomic dysfunction in different subgroups of myasthenia
gravis (MG) patients. Standard cardiovascular reflex tests according to Ewing, spectral and …