Guidance on the management of diarrhoea during cancer chemotherapy

J Andreyev, P Ross, C Donnellan, E Lennan… - The Lancet …, 2014 - thelancet.com
Diarrhoea induced by chemotherapy in cancer patients is common, causes notable
morbidity and mortality, and is managed inconsistently. Previous management guidelines …

[HTML][HTML] Gastro-intestinal toxicity of chemotherapeutics in colorectal cancer: the role of inflammation

CS Lee, EJ Ryan, GA Doherty - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Chemotherapy-induced diarrhea (CID) is a common and often severe side effect
experienced by colorectal cancer (CRC) patients during their treatment. As chemotherapy …

A randomized double-blind controlled trial: impact of probiotics on diarrhea in patients treated with pelvic radiation

M Demers, A Dagnault, J Desjardins - Clinical nutrition, 2014 - Elsevier
Background & aims Radical radiation therapy is commonly used for treatment of pelvic
cancer. Up to 80% of patients receiving radiotherapy will develop acute radiation induced …

Anti-colorectal cancer chemotherapy-induced diarrhoea: current treatments and side-effects

RM McQuade, JC Bornstein… - … Journal of Clinical …, 2014 - info.openarchivespress.com
Chemotherapy-induced diarrhoea (CID) is a common side-effect experienced by patients
being treated with a variety of antineoplastic agents. Approximately 80% of patients …

Irinotecan disrupts tight junction proteins within the gut: implications for chemotherapy-induced gut toxicity

HR Wardill, JM Bowen, N Al-Dasooqi… - Cancer biology & …, 2014 - Taylor & Francis
Chemotherapy for cancer causes significant gut toxicity, leading to severe clinical
manifestations and an increased economic burden. Despite much research, many of the …

Role of nurses in the assessment and management of chemotherapy-related side effects in cancer patients

H Roe, E Lennan - Nursing: Research and Reviews, 2014 - Taylor & Francis
Chemotherapy services in the UK have been the subject of national policy directives for the
past decade. These directives, amongst other things, include the development of nurse-led …

Targeted inhibition of IL‐18 attenuates irinotecan‐induced intestinal mucositis in mice

RCP Lima‐Júnior, HC Freitas… - British journal of …, 2014 - Wiley Online Library
Background and Purpose Intestinal mucositis is a common side‐effect of irinotecan‐based
cancer chemotherapy regimens. This mucositis is associated with cytokine activation and …

Pretreatment with Saccharomyces boulardii does not prevent the experimental mucositis in Swiss mice

TU Maioli, B de Melo Silva, MN Dias, NC Paiva… - Journal of negative …, 2014 - Springer
Abstract Background The antimetabolite chemotherapy 5-Fluorouracil is one of the most
commonly prescribed drugs in clinical cancer treatment. Although this drug is not specific for …

Factors affecting patient's perception of anticancer treatments side-effects: an observational study

S Russo, M Cinausero, L Gerratana… - Expert opinion on …, 2014 - Taylor & Francis
Background: Analysis of relative importance of side effects of anticancer therapy is extremely
useful in the process of clinical decision making. There is evidence that patients' perception …

Fixed ratio (2: 1) prolonged-release oxycodone/naloxone combination improves bowel function in patients with moderate-to-severe pain and opioid-induced …

G Koopmans, K Simpson, J De Andrés… - … medical research and …, 2014 - Taylor & Francis
Objective: The effects of combined oxycodone/naloxone prolonged release tablets (OXN
PR) were investigated in patients with moderate-to-severe chronic cancer-related or non …