Cardiac tissue contains discrete pools of mitochondria that are characterized by their
subcellular spatial arrangement. Subsarcolemmal mitochondria (SSM) exist below the cell …

PGC-1α regulates critical processes in muscle physiology, including mitochondrial
biogenesis, lipid metabolism and angiogenesis. Furthermore, PGC-1α was suggested as an …

Mutations in the human actin depolymerizing factor cofilin2 result in an autosomal dominant
form of nemaline myopathy. Here, we report on the targeted ablation of murine cofilin2 …

Tubulin, a well-known component of the microtubule in the cytoskeleton, has an important
role in the transport and positioning of mitochondria in a cell type dependent manner. This …

Desmin, being a major intermediate filament of mature muscle cell, interacts with
mitochondria within the cell and participates in mitochondria proper localization. The goal of …

Purpose.: To investigate the distribution of the intermediate filament (IF) proteins desmin,
vimentin, and nestin in human extraocular muscles (EOMs). Methods.: Healthy adult EOM …

Animals selected for residual feed intake (RFI) can be used as a model to elucidate
molecular explanations for differences in growth efficiency. The objective of this study was to …

Histological mitochondrial changes are generally found to be associated with late onset
myofibrillar myopathies (MFMs). How these changes contribute to the pathogenesis of MFMs …

Impact of cryopreservation protocols on skeletal muscle mitochondrial respiration remains
controversial. We showed that oxygen consumption with main mitochondrial substrates in rat …

Mucuna pruriens is widely used in traditional medicine for treatments of various diseases. In
certain region of Nigeria, the seed is used as oral prophylactics for snakebite. Rats …