The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs)

G Morris, M Berk, P Galecki, M Maes - Molecular neurobiology, 2014 - Springer
Abstract The World Health Organization classifies myalgic encephalomyelitis/chronic fatigue
syndrome (ME/cfs) as a nervous system disease. Together with other diseases under the …

CD56brightperforinlow noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via …

P Carrega, I Bonaccorsi, E Di Carlo… - The Journal of …, 2014 - journals.aai.org
As limited information is available regarding the distribution and trafficking of NK cells
among solid organs, we have analyzed a wide array of tissues derived from different human …

Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity

H Ham, DD Billadeau - Frontiers in immunology, 2014 - frontiersin.org
Natural killer (NK) cells are lymphocytes of the innate immune system that secrete cytokines
upon activation and mediate the killing of tumor cells and virus-infected cells, especially …

Accumulation of natural killer cells in ischemic brain tissues and the chemotactic effect of IP-10

Y Zhang, Z Gao, D Wang, T Zhang, B Sun, L Mu… - Journal of …, 2014 - Springer
Background Stroke is accompanied by a distinguished inflammatory reaction that is initiated
by the infiltration of immunocytes, expression of cytokines, and other inflammatory …

Vitamin D3 deficiency results in dysfunctions of immunity with severe fatigue and depression in a variety of diseases

AD Hoeck - in vivo, 2014 - iv.iiarjournals.org
Recent immune data on vitamin D3 deficiency help to more clearly understand chronic
fatiguing illnesses, such as autoimmune disorders, cancer and chronic fatigue syndrome …

[PDF][PDF] The roles of innate lymphoid cells in the development of asthma

Y Woo, D Jeong, DH Chung, HY Kim - Immune network, 2014 - synapse.koreamed.org
Traditionally, most scientists believed that asthma was an immunological disease mainly
mediated by Th2 cells and the adaptive immune system (1). Indeed, Th2 cells do play a …

In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection

Y Takahashi, SN Byrareddy, C Albrecht… - PLoS …, 2014 - journals.plos.org
The studies reported herein are the first to document the effect of the in vivo administration of
a JAK3 inhibitor for defining the potential role of NK cells during acute SIV infection of a …

Mature resting Ly6Chigh natural killer cells can be reactivated by IL‐15

A Omi, Y Enomoto, T Kiniwa, N Miyata… - European journal of …, 2014 - Wiley Online Library
Mature NK cells are heterogeneous as to their expression levels of cell surface molecules.
However, the functional differences and physiological roles of each NK‐cell subset are not …

Genkwadaphnin induces IFN-γ via PKD1/NF-κB/STAT1 dependent pathway in NK-92 cells

HB Kang, KS Ahn, SR Oh, JW Kim - PLoS One, 2014 - journals.plos.org
The flower buds of Daphne genkwa Sieb. et Zucc. have been used as a traditional Chinese
medicine although their functional mechanisms have not been discovered yet. We have …

HINT1 peptide/Hsp70 complex induces NK‐cell‐dependent immunoregulation in a model of autoimmune demyelination

G Galazka, A Jurewicz, M Domowicz… - European Journal of …, 2014 - Wiley Online Library
Heat shock proteins (Hsps) interact with the immune system and have been shown to
contribute to immunoregulation. As efficient chaperones, Hsps bind many peptides and …