Shift work comprises work schedules that extend beyond the typical “nine-to-five” workday,
wherein schedules often comprise early work start, compressed work weeks with 12-hour …

Breast cancer is the leading cause of cancer death among women worldwide, and there is
only a limited explanation of why. Risk is highest in the most industrialized countries but also …

Physiological processes such as the sleep-wake cycle, metabolism and hormone secretion
are controlled by a circadian rhythm adapted to 24 h day-night periodicity. This circadian …

Night shift work has been associated with an increased risk of breast cancer pointing to a
role of circadian disruption. We investigated the role of circadian clock gene polymorphisms …

Purpose There is growing evidence that circadian disruption may alter risk and
aggressiveness of cancer. We evaluated common genetic variants in the circadian gene …

Background Evidence for the carcinogenicity of shift work in humans is limited because of
significant heterogeneity of the results, thus more in-depth research in needed. The …

In the past 20 years both the circadian clock and endoplasmic reticulum (ER) stress
signaling have emerged as major players in oncogenesis and cancer development …

Background: This study examined a PERIOD3 (PER3) gene variable number tandem repeat
polymorphism and chronotype as potential BrCA risk factors among Indian women …

The uneventful progression through the cell cycle is closely associated with the rhythm set
by the circadian clock machinery, with the S-phase of the cell cycle typically occurring at …

It is well established that the incidence and infarct size in acute myocardial infarction (AMI) is
subject to circadian variations. At the molecular level, circadian clocks in distinct cells …