Objective: We compared mindfulness-based cognitive therapy (MBCT) with both cognitive
psychological education (CPE) and treatment as usual (TAU) in preventing relapse to major …

BackgroundResearch on gene× environment interaction in major depressive disorder
(MDD) has thus far primarily focused on candidate genes, although genetic effects are …

Cognitive-behavioural therapy (CBT) is an empirically supported treatment for anxiety
disorders. CBT treatments are based on disorder-specific protocols that have been …

Scarce evidence suggests that inflammatory and metabolic dysregulation predicts poor
response to antidepressants, which could result in worse depression outcome. This study …

Background Psychiatric comorbidities are common in major depressive disorder (MDD).
They may worsen outcome and cause economic burden. The primary objective was to …

Background This study compares disability levels between different anxiety disorders and
healthy controls. We further investigate the role of anxiety arousal and avoidance behaviour …

Objective Understanding chronicity in OCD is hampered by contradictory findings arising
from dissimilar definitions of chronic OCD. The purpose of this study was to investigate the …

Objective: Anxiety disorders have been shown to differ in their course, but it is unknown
whether DSM-categories represent clinically relevant course trajectories. We aim to identify …

Background Depression is common in people with coronary heart disease (CHD) and
associated with worse outcome. This study explored the acceptability and feasibility of …

Background Although depressed and anxious patients often show an unhealthy lifestyle,
much is still unclear about its impact on the natural course of disorders. This study will …