[HTML][HTML] Therapeutic applications of curcumin for patients with pancreatic cancer

M Kanai - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
A number of preclinical studies have demonstrated anticancer effects for curcumin in various
types of tumors, including pancreatic cancer. Curcumin has anticancer effects both alone …

Meta-analysis shows clinically relevant and long-lasting deterioration in health-related quality of life after esophageal cancer surgery

M Jacobs, RC Macefield, RG Elbers, K Sitnikova… - Quality of life …, 2014 - Springer
Purpose The purpose of the study is to (1) estimate the direction, clinical relevance, and
duration of health-related quality of life (HRQL) change in the first year following esophageal …

Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma …

H Wilke, K Muro, E Van Cutsem, SC Oh… - The lancet …, 2014 - thelancet.com
Background VEGFR-2 has a role in gastric cancer pathogenesis and progression. We
assessed whether ramucirumab, a monoclonal antibody VEGFR-2 antagonist, in …

Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 …

M Donker, G van Tienhoven, ME Straver… - The lancet …, 2014 - thelancet.com
Background If treatment of the axilla is indicated in patients with breast cancer who have a
positive sentinel node, axillary lymph node dissection is the present standard. Although …

Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6) …

YL Wu, C Zhou, CP Hu, J Feng, S Lu, Y Huang… - The lancet …, 2014 - thelancet.com
Background Afatinib—an oral irreversible ErbB family blocker—improves progression-free
survival compared with pemetrexed and cisplatin for first-line treatment of patients with …

Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised …

CS Fuchs, J Tomasek, CJ Yong, F Dumitru… - The Lancet, 2014 - thelancet.com
Background Vascular endothelial growth factor (VEGF) and VEGF receptor-2 (VEGFR-2)-
mediated signalling and angiogenesis can contribute to the pathogenesis and progression …

[HTML][HTML] Baseline characteristics and disease burden in patients in the International Paroxysmal Nocturnal Hemoglobinuria Registry

H Schrezenmeier, P Muus, G Socié, J Szer… - …, 2014 - ncbi.nlm.nih.gov
Paroxysmal nocturnal hemoglobinuria is a rare, acquired disease associated with hemolytic
anemia, bone marrow failure, thrombosis, and, frequently, poor quality of life. The …

Lymphedema after surgery for endometrial cancer: prevalence, risk factors, and quality of life

KJ Yost, AL Cheville, MM Al-Hilli, A Mariani… - Obstetrics & …, 2014 - journals.lww.com
OBJECTIVE: To estimate lower extremity lymphedema prevalence in patients surgically
treated for endometrial cancer, identify predictors of lymphedema, and evaluate the effects of …

Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial

E Chow, YM van der Linden, D Roos… - The Lancet …, 2014 - thelancet.com
Background Although repeat radiation treatment has been shown to palliate pain in patients
with bone metastases from multiple primary origin sites, data for the best possible dose …

Efficacy of methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: a randomized, placebo-controlled, double-blind trial

Ø Paulsen, P Klepstad, JH Rosland, N Aass… - Journal of Clinical …, 2014 - ascopubs.org
Purpose Corticosteroids are frequently used in cancer pain management despite limited
evidence. This study compares the analgesic efficacy of corticosteroid therapy with placebo …