Biosensor-based microRNA detection: techniques, design, performance, and challenges

BN Johnson, R Mutharasan - Analyst, 2014 - pubs.rsc.org
The current state of biosensor-based techniques for amplification-free microRNA (miRNA)
detection is critically reviewed. Comparison with non-sensor and amplification-based …

Application of nucleic acid–lipid conjugates for the programmable organisation of liposomal modules

PA Beales, TK Vanderlick - Advances in colloid and interface science, 2014 - Elsevier
We present a critical review of recent work related to the assembly of multicompartment
liposome clusters using nucleic acids as a specific recognition unit to link liposomal …

[HTML][HTML] Coarse-grained modeling of DNA curvature

GS Freeman, DM Hinckley, JP Lequieu… - The Journal of …, 2014 - pubs.aip.org
The interaction of DNA with proteins occurs over a wide range of length scales, and
depends critically on its local structure. In particular, recent experimental work suggests that …

Sensing viruses by mechanical tension of DNA in responsive hydrogels

J Shin, AG Cherstvy, R Metzler - Physical Review X, 2014 - APS
The rapid worldwide spread of severe viral infections, often involving novel mutations of
viruses, poses major challenges to our health-care systems. This means that tools that can …

Antisense oligonucleotide-stimulated transcriptional pausing reveals RNA exit channel specificity of RNA polymerase and mechanistic contributions of NusA and RfaH

KE Kolb, PP Hein, R Landick - Journal of Biological Chemistry, 2014 - ASBMB
Transcript elongation by bacterial RNA polymerase (RNAP) is thought to be regulated at
pause sites by open versus closed positions of the RNAP clamp domain, pause-suppressing …

Mitogenomic data resolve basal relationships among passeriform and passeridan birds

FK Barker - Molecular phylogenetics and evolution, 2014 - Elsevier
Passerine birds compose over half of avian species diversity and exhibit an impressive array
of phenotypic variation of interest to evolutionary biologists. Although this group has long …

Twist versus nonlinear stacking in short DNA molecules

M Zoli - Journal of theoretical biology, 2014 - Elsevier
The denaturation of the double helix is a template for fundamental biological functions such
as replication and transcription involving the formation of local fluctuational openings. The …

[HTML][HTML] Thermal properties of a DNA denaturation with solvent interaction

DX Macedo, I Guedes, EL Albuquerque - Physica A: Statistical Mechanics …, 2014 - Elsevier
In this work we study the effects of the solvent interaction on the nonlinear dynamical
structure of a DNA segment, by using a time-independent perturbation approach …

[HTML][HTML] Insights into DNA-mediated interparticle interactions from a coarse-grained model

Y Ding, J Mittal - The Journal of Chemical Physics, 2014 - pubs.aip.org
DNA-functionalized particles have great potential for the design of complex self-assembled
materials. The major hurdle in realizing crystal structures from DNA-functionalized particles …

Thermal stability of DNA origami on mica

MA Pillers, M Lieberman - Journal of Vacuum Science & Technology B, 2014 - pubs.aip.org
The authors report the unusual thermal stability of deoxyribose nucleic acid (DNA) origami
when adhered to a solid substrate. Even when heated to 150 C for 45 min, these DNA …