[HTML][HTML] Ischemia/reperfusion activates myocardial innate immune response: the key role of the toll-like receptor

G Vilahur, L Badimon - Frontiers in physiology, 2014 - frontiersin.org
Recent data have indicated that the myocardium may act as an immune organ initiating
cardiac innate immune response and inflammation. It has been suggested that activation of …

Innate immunity and cardiomyocytes in ischemic heart disease

L Lin, AA Knowlton - Life sciences, 2014 - Elsevier
Myocardial ischemia/reperfusion (I/R) is the most common cause of myocardial
inflammation, which is primarily a manifestation of the innate immune responses. Innate …

Laparoscopic sleeve gastrectomy ameliorates mRNA expression of inflammation-related genes in subcutaneous adipose tissue but not in peripheral monocytes of …

P Trachta, I Dostalova, D Haluzikova… - Molecular and cellular …, 2014 - Elsevier
Low-grade inflammation links obesity, insulin resistance, and cardiovascular diseases. We
investigated the effects of laparoscopic sleeve gastrectomy (LSG) on expression profile of …

Protein kinase Cε-calcineurin cosignaling downstream of toll-like receptor 4 downregulates fibrosis and induces wound healing gene expression in cardiac …

RFDS Mesquita, MA Paul, A Valmaseda… - … and Cellular Biology, 2014 - Am Soc Microbiol
The pathways which regulate resolution of inflammation and contribute to positive
remodeling of the myocardium following injury are poorly understood. Here we show that …

Innate immune inflammatory response in the acutely ischemic myocardium

S Deftereos, C Angelidis, G Bouras… - Medicinal …, 2014 - ingentaconnect.com
The “holy grail” of modern interventional cardiology is the salvage of viable myocardial
tissue in the distribution of an acutely occluded coronary artery. Thrombolysis and …

Postconditioning with a CpG containing oligodeoxynucleotide ameliorates myocardial infarction in a murine closed-chest model

SC Kim, S Wu, X Fang, J Neumann, L Eichhorn… - Life sciences, 2014 - Elsevier
Aims Toll-like receptor (TLR) 9 ligand CpG-oligodeoxynucleotide (CpG-ODN) exerts
preconditioning in myocardial ischemia/reperfusion. We hypothesized a postconditioning …

HMGB1-TLR4 促进缺氧复氧介导的大鼠肾小管上皮细胞凋亡

尹金凤, 刘秀娟, 沈江山, 周阳… - 基础医学与 …, 2014 - journal11.magtechjournal.com
目的研究缺氧复氧后大鼠肾小管上皮细胞中高迁移率族蛋白1 (HMGB1) 和Toll 样受体4 (TLR4)
的表达及其在肾小管上皮细胞凋亡中的调控机制方法大鼠原代肾小管上皮细胞(PTECs) 置于6 …

Επίδραση της ισχαιμικής προετοιμασίας του εντέρου με ή χωρίς τη χορήγηση της αντιθρομβίνης στη βλάβη των νεφρών μετά από ισχαιμία/επαναιμάτωση του λεπτού …

ΓΕ Ρόϊδος - 2014 - ikee.lib.auth.gr
Εισαγωγή: Οι βλάβες που προκαλούνται μετά από οξεία ισχαιμία-επαναιμάτωση του εντέρου
αποτελούν ένα ιδιαίτερα σημαντικό πρόβλημα στην καθημερινή ιατρική πράξη, τόσο …