Genome-wide association study identifies multiple loci associated with bladder cancer risk
JD Figueroa, Y Ye, A Siddiq… - Human molecular …, 2014 - academic.oup.com
Candidate gene and genome-wide association studies (GWAS) have identified 11
independent susceptibility loci associated with bladder cancer risk. To discover additional …
independent susceptibility loci associated with bladder cancer risk. To discover additional …
[HTML][HTML] Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin–proteasome pathway
N Ohoka, K Nagai, T Hattori, K Okuhira, N Shibata… - Cell death & …, 2014 - nature.com
The selective degradation of target proteins with small molecules is a novel approach to the
treatment of various diseases, including cancer. We have developed a protein knockdown …
treatment of various diseases, including cancer. We have developed a protein knockdown …
Nucleic acid-based tissue biomarkers of urologic malignancies
D Dietrich, S Meller, B Uhl, B Ralla… - Critical reviews in …, 2014 - Taylor & Francis
Molecular biomarkers play an important role in the clinical management of cancer patients.
Biomarkers allow estimation of the risk of developing cancer; help to diagnose a tumor …
Biomarkers allow estimation of the risk of developing cancer; help to diagnose a tumor …
[HTML][HTML] MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44
G Yu, W Yao, W Xiao, H Li, H Xu, B Lang - Journal of experimental & …, 2014 - Springer
Background Metastasis have considered as an important clinical obstacle in the treatment of
human cancer including bladder cancer. Post-transcriptional regulation has emerged as …
human cancer including bladder cancer. Post-transcriptional regulation has emerged as …
Molecular biomarkers for predicting outcomes in urothelial carcinoma of the bladder
N Sapre, P Herle, PD Anderson… - Pathology-Journal of …, 2014 - journals.lww.com
Molecular biomarkers are used routinely in the clinical management of several tumours such
as prostate, colon, ovarian and pancreatic cancer but management decisions in bladder …
as prostate, colon, ovarian and pancreatic cancer but management decisions in bladder …
Genome-wide association study yields variants at 20p12. 2 that associate with urinary bladder cancer
T Rafnar, P Sulem, G Thorleifsson… - Human molecular …, 2014 - academic.oup.com
Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded
common variants at 12 loci that associate with risk of the disease. We report here the results …
common variants at 12 loci that associate with risk of the disease. We report here the results …
Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai
R Corral, JP Lewinger, D Van Den Berg… - … journal of cancer, 2014 - Wiley Online Library
Tobacco smoking is a bladder cancer risk factor and a source of carcinogens that induce
DNA damage to urothelial cells. Using data and samples from 988 cases and 1,004 controls …
DNA damage to urothelial cells. Using data and samples from 988 cases and 1,004 controls …
A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells
R Yao, Y Kondoh, Y Natsume, H Yamanaka, M Inoue… - Oncogene, 2014 - nature.com
The mitotic spindle is assembled by the coordinated action of centrosomes and kinetochore
microtubules. An evolutionally conserved protein family, transforming acidic coiled-coil …
microtubules. An evolutionally conserved protein family, transforming acidic coiled-coil …
Cumulative effect of genome‐wide association study‐identified genetic variants for bladder cancer
M Wang, H Chu, Q Lv, L Wang, L Yuan… - … journal of cancer, 2014 - Wiley Online Library
Recent genome‐wide association studies have identified 14 genetic variants associated
with bladder cancer in Caucasians. The effects of these risk variants and their cumulative …
with bladder cancer in Caucasians. The effects of these risk variants and their cumulative …
Genetic score of multiple risk‐associated single nucleotide polymorphisms is a marker for genetic susceptibility to bladder cancer
P Wang, D Ye, J Guo, F Liu, H Jiang… - Genes …, 2014 - Wiley Online Library
Genome‐wide association studies have identified 13 single nucleotide polymorphisms
(SNPs) that are associated with bladder cancer; three of these SNPs were validated in the …
(SNPs) that are associated with bladder cancer; three of these SNPs were validated in the …