Candidate gene and genome-wide association studies (GWAS) have identified 11
independent susceptibility loci associated with bladder cancer risk. To discover additional …

The selective degradation of target proteins with small molecules is a novel approach to the
treatment of various diseases, including cancer. We have developed a protein knockdown …

Molecular biomarkers play an important role in the clinical management of cancer patients.
Biomarkers allow estimation of the risk of developing cancer; help to diagnose a tumor …

Background Metastasis have considered as an important clinical obstacle in the treatment of
human cancer including bladder cancer. Post-transcriptional regulation has emerged as …

Molecular biomarkers are used routinely in the clinical management of several tumours such
as prostate, colon, ovarian and pancreatic cancer but management decisions in bladder …

Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded
common variants at 12 loci that associate with risk of the disease. We report here the results …

Tobacco smoking is a bladder cancer risk factor and a source of carcinogens that induce
DNA damage to urothelial cells. Using data and samples from 988 cases and 1,004 controls …

The mitotic spindle is assembled by the coordinated action of centrosomes and kinetochore
microtubules. An evolutionally conserved protein family, transforming acidic coiled-coil …

Recent genome‐wide association studies have identified 14 genetic variants associated
with bladder cancer in Caucasians. The effects of these risk variants and their cumulative …

Genome‐wide association studies have identified 13 single nucleotide polymorphisms
(SNPs) that are associated with bladder cancer; three of these SNPs were validated in the …