MALDI TOF imaging mass spectrometry in clinical pathology: a valuable tool for cancer diagnostics
J Kriegsmann, M Kriegsmann… - … journal of oncology, 2014 - spandidos-publications.com
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …
Chemo-and bioinformatics resources for in silico drug discovery from medicinal plants beyond their traditional use: a critical review
Covering: up to 2014 In silico approaches have been widely recognised to be useful for drug
discovery. Here, we consider the significance of available databases of medicinal plants and …
discovery. Here, we consider the significance of available databases of medicinal plants and …
Optimization and comparison of multiple MALDI matrix application methods for small molecule mass spectrometric imaging
E Gemperline, S Rawson, L Li - Analytical chemistry, 2014 - ACS Publications
The matrix application technique is critical to the success of a matrix-assisted laser
desorption/ionization (MALDI) experiment. This work presents a systematic study aiming to …
desorption/ionization (MALDI) experiment. This work presents a systematic study aiming to …
A critical evaluation of the current state-of-the-art in quantitative imaging mass spectrometry
SR Ellis, AL Bruinen, RMA Heeren - Analytical and bioanalytical chemistry, 2014 - Springer
Mass spectrometry imaging (MSI) has evolved into a valuable tool across many fields of
chemistry, biology, and medicine. However, arguably its greatest disadvantage is the …
chemistry, biology, and medicine. However, arguably its greatest disadvantage is the …
Recent methodological advances in MALDI mass spectrometry
K Dreisewerd - Analytical and bioanalytical chemistry, 2014 - Springer
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used
for characterization of large, thermally labile biomolecules. Advantages of this analytical …
for characterization of large, thermally labile biomolecules. Advantages of this analytical …
Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis
JG Swales, JW Tucker, N Strittmatter, A Nilsson… - Analytical …, 2014 - ACS Publications
Cassette dosing of compounds for preclinical drug plasma pharmacokinetic analysis has
been shown to be a powerful strategy within the pharmaceutical industry for increasing …
been shown to be a powerful strategy within the pharmaceutical industry for increasing …
Multicenter matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma
TJA Dekker, BD Balluff, EA Jones… - Journal of proteome …, 2014 - ACS Publications
MALDI mass spectrometry imaging (MSI) has rapidly established itself as a powerful
biomarker discovery tool. To date, no formal investigation has assessed the center-to-center …
biomarker discovery tool. To date, no formal investigation has assessed the center-to-center …
Lipidomics in situ: insights into plant lipid metabolism from high resolution spatial maps of metabolites
PJ Horn, KD Chapman - Progress in Lipid Research, 2014 - Elsevier
The emergence of 'omics' technologies (ie genomics, proteomics, metabolomics, etc.) have
revealed new avenues for exploring plant metabolism through data-rich experimentation …
revealed new avenues for exploring plant metabolism through data-rich experimentation …
New insights into the structural and spatial variability of cell-wall polysaccharides during wheat grain development, as revealed through MALDI mass spectrometry …
D Veličković, D Ropartz, F Guillon… - Journal of …, 2014 - academic.oup.com
Abstract Arabinoxylans (AX) and (1→ 3),(1→ 4)-β-glucans (BG) are the major components of
wheat grain cell walls. Although incompletely described at the molecular level, it is known …
wheat grain cell walls. Although incompletely described at the molecular level, it is known …
Label-Free in Situ Monitoring of Histone Deacetylase Drug Target Engagement by Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Biotyping and …
B Munteanu, B Meyer, C von Reitzenstein… - Analytical …, 2014 - ACS Publications
Measurements of target activation in cells or tissues are key indicators of efficacy during
drug development. In contrast to established methods that require reagents and multiple …
drug development. In contrast to established methods that require reagents and multiple …