Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …

Covering: up to 2014 In silico approaches have been widely recognised to be useful for drug
discovery. Here, we consider the significance of available databases of medicinal plants and …

The matrix application technique is critical to the success of a matrix-assisted laser
desorption/ionization (MALDI) experiment. This work presents a systematic study aiming to …

Mass spectrometry imaging (MSI) has evolved into a valuable tool across many fields of
chemistry, biology, and medicine. However, arguably its greatest disadvantage is the …

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used
for characterization of large, thermally labile biomolecules. Advantages of this analytical …

Cassette dosing of compounds for preclinical drug plasma pharmacokinetic analysis has
been shown to be a powerful strategy within the pharmaceutical industry for increasing …

MALDI mass spectrometry imaging (MSI) has rapidly established itself as a powerful
biomarker discovery tool. To date, no formal investigation has assessed the center-to-center …

The emergence of 'omics' technologies (ie genomics, proteomics, metabolomics, etc.) have
revealed new avenues for exploring plant metabolism through data-rich experimentation …

Abstract Arabinoxylans (AX) and (1→ 3),(1→ 4)-β-glucans (BG) are the major components of
wheat grain cell walls. Although incompletely described at the molecular level, it is known …

Measurements of target activation in cells or tissues are key indicators of efficacy during
drug development. In contrast to established methods that require reagents and multiple …