Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies

M Maccarrone, M Guzmán, K Mackie… - Nature Reviews …, 2014 - nature.com
Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …

Extracellular signals controlling neuroblast migration in the postnatal brain

G Lalli - Cellular and Molecular Control of Neuronal Migration, 2014 - Springer
The most prominent example of long-distance migration in the postnatal brain is the rostral
migratory stream (RMS) formed by neuroblasts originating in the subventricular zone (SVZ) …

Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells

R Ramer, S Fischer, M Haustein, K Manda… - Biochemical …, 2014 - Elsevier
Cannabinoids inhibit tumor neovascularization as part of their tumorregressive action.
However, the underlying mechanism is still under debate. In the present study the impact of …

RalA promotes a direct exocyst–Par6 interaction to regulate polarity in neuronal development

A Das, S Gajendra, K Falenta, MJ Oudin… - Journal of cell …, 2014 - journals.biologists.com
Cell polarization is essential for neuronal development in both the embryonic and postnatal
brain. Here, using primary cultures, in vivo postnatal electroporation and conditional genetic …

Endocannabinoid signalling in neuronal migration

Y Zhou, K Falenta, G Lalli - The International Journal of Biochemistry & Cell …, 2014 - Elsevier
The endocannabinoid (eCB) system consists of several endogenous lipids, their target CB1
and CB2 receptors and enzymes responsible for their synthesis and degradation. The most …

Cannabis, cannabinoids, and the association with psychosis

R Radhakrishnan, PH Addy, RA Sewell… - The effects of drug …, 2014 - Elsevier
Recent advances in knowledge about cannabinoid receptor function have renewed interest
in the association between cannabis and psychosis. Converging lines of evidence suggest …

Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina

B Cécyre, M Monette, L Beudjekian… - Frontiers in …, 2014 - frontiersin.org
In recent decades, there has been increased interest in the physiological roles of the
endocannabinoid (eCB) system and its receptors, the cannabinoid receptor types 1 (CB1R) …

Effects of cannabis and cannabinoids in the human nervous system

H Kalant - The effects of drug abuse on the human nervous …, 2014 - Elsevier
The endocannabinoid (EC) system, consisting of ECs, their synthesizing and degrading
enzymes, specific transmembrane EC transporters and receptors, is located in both …

Progress of in vivo electroporation in the rodent brain

XF Ding, DL Ma, Q Zhang, W Peng, M Fan… - Current Gene …, 2014 - ingentaconnect.com
In vivo electroporation is one of the most efficient methods for introducing the nucleic acids
into the target tissues, and thus plays a pivotal role in gene therapeutic studies. In vivo …