Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

In the last century, vaccination has been the most effective medical intervention to reduce
death and morbidity caused by infectious diseases. It is believed that vaccines save at least …

Vaccines have a history that started late in the 18th century. From the late 19th century,
vaccines could be developed in the laboratory. However, in the 20th century, it became …

Vaccination, which is the most effective medical intervention that has ever been introduced,
originated from the observation that individuals who survived a plague or smallpox would …

One of the exciting aspects of being involved in the field of molecular biology is the ever-
accelerating rate of progress, both in the development of new methodologies and the …

Surface proteins play a critical role in the interaction between cells and their environment, as
they take part in processes like signaling, adhesion, transport, etc. In pathogenic …

Neisseria meningitidis causes globally 1· 2 million invasive disease cases and 135 000
deaths per year, mostly in infants and adolescents. A century of traditional vaccinology had …

Highlights•Immunosenescence leads to increased susceptibility to infection and decreased
vaccine response.•Heme-oxygenase gene expression may be an important element in age …

Abstract The integrative Vaccine Investigation and Online Information Network (VIOLIN)
vaccine research database and analysis system (http://www. violinet. org) curates, stores …

We present Vacceed, a highly configurable and scalable framework designed to automate
the process of high-throughput in silico vaccine candidate discovery for eukaryotic …